Evidence map›Paper›PMID 39168156›Full record

ArticlePhysics in medicine and biology2024

PETcoil: first results from a second-generation RF-penetrable TOF-PET brain insert for simultaneous PET/MRI.

Qian Dong, Muhammad Nasir Ullah, Derek Innes, Ronald D Watkins, Chen-Ming Chang, Sarah J Zou, Andrew Groll, Ilaria Sacco, Garry Chinn, Craig S Levin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physics in medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qian DongMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.ORCID 0000-0002-4250-7788
Muhammad Nasir UllahMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.ORCID 0000-0002-3088-3225
Derek InnesMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.
Ronald D WatkinsMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.ORCID 0009-0005-2168-2519
Chen-Ming ChangMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.
Sarah J ZouMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.ORCID 0009-0007-5275-9739
Andrew GrollMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.ORCID 0000-0001-7973-0206
Ilaria SaccoMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.
Garry ChinnMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.
Craig S LevinMolecular Imaging Instrumentation Laboratory, Department of Radiology, Stanford University, Stanford, CA, United States of America.ORCID 0000-0002-4575-5074

Funding

RF-penetrable PET ring for acquiring simultaneous time-of-flight PET and MRI dataR01EB019465 · NIBIB · STANFORD UNIVERSITY · PI LEVIN, CRAIG S · 2015 to 2021
$2.9M
Translation and Validation of a Radiofrequency-Penetrable PET insert for Simultaneous PET/MRI imaging of Neurological DisordersR01EB031038 · NIBIB · STANFORD UNIVERSITY · PI LEVIN, CRAIG S · 2022 to 2025
$2.3M
NIBIB NIH HHS R01 EB019465NIBIB NIH HHS R01 EB031038
6 · The paper itself

Abstract

Simultaneous positron emission tomography (PET)/magnetic resonance imaging provides concurrent information about anatomic, functional, and molecular changes in disease. We are developing a second generation MR-compatible RF-penetrable TOF-PET insert. The insert has a smaller scintillation crystal size and ring diameter compared to clinical whole-body PET scanners, resulting in higher spatial resolution and sensitivity. This paper reports the initial system performance of this full-ring PET insert. The global photopeak energy resolution and global coincidence time resolution, 11.74 ± 0.03 % FWHM and 238.1 ± 0.5 ps FWHM, respectively, are preserved as we scaled up the system to a full ring comprising 12, 288 LYSO-SiPM channels (crystal size: 3.2 × 3.2 × 20 mm

Indexed as

BrainMagnetic Resonance ImagingPhantoms, ImagingPositron-Emission TomographyHumansImage Processing, Computer-AssistedMultimodal ImagingRadio WavesTime FactorsMR-compatiblePET insertRF-penetrablesimultaneous PET/MRITOF

Identifiers

PMID39168156
PMCPMC12967323

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.