Evidence map›Paper›PMID 39167603›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Schlank orchestrates insect developmental transition by switching H3K27 acetylation to trimethylation in the prothoracic gland.

Dongqin Yuan, Xing Zhang, Yan Yang, Ling Wei, Hao Li, Tujing Zhao, Mengge Guo, Zheng Li, Zhu Huang, Min Wang and 5 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dongqin YuanIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0000-0002-9908-9353
Xing ZhangIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Yan YangIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0000-0002-3277-978X
Ling WeiSchool of Life Sciences, Southwest University, Chongqing 400715, China.ORCID 0000-0002-7461-9397
Hao LiIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Tujing ZhaoIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0000-0003-3325-4480
Mengge GuoIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Zheng LiIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0000-0002-7803-5401
Zhu HuangIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Min WangIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Zongcai DaiIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Peixin LiIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Qingyou XiaIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Wenliang QianIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Daojun ChengIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0000-0002-4612-0046

Funding

Municipal Graduate Student Research Innovation Project of Chongqing Municipality CYB23160National Natural Science Fundation of China 32070496National Natural Science Fundation of China 32200404National Natural Science Fundation of China 32370555Natural Science Foundation of Chongqing Municipality (2022NSCQ-MSX3269
6 · The paper itself

Abstract

Insect developmental transitions are precisely coordinated by ecdysone and juvenile hormone (JH). We previously revealed that accumulated H3K27 trimethylation (H3K27me3) at the locus encoding JH signal transducer Hairy is involved in the larval-pupal transition in insects, but the underlying mechanism remains to be fully defined. Here, we show in

Indexed as

Drosophila ProteinsEcdysoneGene Expression Regulation, DevelopmentalHistonesLarvaAcetylationAnimalsBasic Helix-Loop-Helix ProteinsBombyxDrosophila melanogasterHistone DeacetylasesInsect ProteinsJuvenile HormonesMethylationPupaRepressor ProteinsBasic Helix-Loop-Helix ProteinsDrosophila ProteinsEcdysonehairy protein, DrosophilaHistone DeacetylasesHistonesInsect ProteinsJuvenile HormonesRepressor ProteinsTranscription Factorsdevelopmental transitionepigenetic switchH3K27 modificationshormone actionsSchlank

Identifiers

PMID39167603
PMCPMC11363265

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.