Evidence map›Paper›PMID 39167499›Full record

ArticleESC heart failure2024

Transcatheter aortic valve implantation for combined aortic and mitral stenoses: Insights from the OCEAN-TAVI Registry.

Nahoko Kato, Minoru Tabata, Masahiko Noguchi, Joji Ito, Kotaro Obunai, Hiroyuki Watanabe, Fumiaki Yashima, Shinichi Shirai, Norio Tada, Toru Naganuma and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Nahoko KatoDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Japan.ORCID https://orcid.org/0000-0003-0892-4366
Minoru TabataDepartment of Cardiovascular Surgery, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Masahiko NoguchiDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Japan.
Joji ItoDepartment of Cardiovascular surgery, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Japan.
Kotaro ObunaiDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Japan.
Hiroyuki WatanabeDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Japan.
Fumiaki YashimaDepartment of Cardiology, Saiseikai Utsunomiya Hospital, Utsunomiya, Japan.
Shinichi ShiraiDepartment of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.
Norio TadaDepartment of Cardiology, Sendai Kosei Hospital, Sendai, Japan.
Toru NaganumaDepartment of Cardiology, New Tokyo Hospital, Matsudo, Japan.
Masahiro YamawakiDepartment of Cardiology, Saiseikai Yokohama City Eastern Hospital, Yokohama, Japan.
Futoshi YamanakaDepartment of Cardiology, Shonan Kamakura General Hospital, Kamakura, Japan.
Hiroshi UenoSecond Department of Internal Medicine, Toyama University Hospital, Toyama, Japan.
Yohei OhnoDepartment of Cardiology, Tokai University School of Medicine, Isehara, Japan.
Masaki IzumoDepartment of Cardiology, St. Marianna University School of Medicine, Kawasaki, Japan.
Hidetaka NishinaDepartment of Cardiology, Tsukuba Medical Center Hospital, Tsukuba, Japan.
Masahiko AsamiDivision of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan.
Yusuke WatanabeDepartment of Cardiology, Teikyo University School of Medicine, Tokyo, Japan.
Masanori YamamotoDepartment of Cardiology, Toyohashi Heart Center, Toyohashi, Japan.
Toshiaki OtsukaDepartment of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan.
Kentaro HayashidaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
OCEAN‐TAVI investigators

Funding

AbbottBoston ScientificDaiichi SankyoEdwards LifesciencesMedtronic
6 · The paper itself

Abstract

aimsMitral stenosis (MS) occasionally coexists with aortic stenosis (AS). Limited data are available regarding the functional class and clinical outcomes of patients who undergo transcatheter aortic valve implantation (TAVI) for combined AS and MS. This study compared the clinical outcomes in patients with and without MS who underwent TAVI for severe AS and assessed the impact of mitral annulus calcification (MAC) severity, transmitral gradient (TMG) and mitral valve area (MVA) on outcomes in patients with combined AS and MS.

methodsWe investigated patients in the OCEAN-TAVI registry who underwent TAVI. MS was defined as an MVA ≤ 1.5 cm

resultsWe identified 106 patients with MS (MAC 84%; TMG 6.4 ± 2.6 mmHg; MVA 1.10 ± 0.31 cm

conclusionsIn patients undergoing TAVI for severe AS, those with moderate or severe MS experienced worse outcomes after TAVI compared with those without MS. Patients with combined AS and MS sustained symptom improvement at 1-year post-TAVI. MAC severity was a useful predictor of adverse events compared with MS haemodynamics such as TMG and MVA in patients with combined AS and MS.

Indexed as

Aortic Valve StenosisMitral Valve StenosisRegistriesTranscatheter Aortic Valve ReplacementAged, 80 and overAortic ValveFemaleFollow-Up StudiesHumansMaleMitral ValveRetrospective StudiesSeverity of Illness IndexSurvival RateTreatment Outcomeaortic stenosismitral annulus calcificationmitral stenosistranscatheter aortic valve implantation

Identifiers

PMID39167499
PMCPMC11631303

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.