Evidence map›Paper›PMID 39167317›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024

Life's Essential 8 and its association with osteoarthritis and disability: a cross-sectional study based on the NHANES 2005-2018 database.

Mi Chen, Yuebai Chen, Chao Li

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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1 · What the graph read from it

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4 citing papers in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Mi ChenDepartment of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China.ORCID https://orcid.org/0000-0003-2024-3563
Yuebai ChenFaculty of Science, McGill University, Montreal, QC, Canada.ORCID https://orcid.org/0009-0009-4238-5803
Chao LiDepartment of Respiration, The First Affiliated Hospital of Xinjiang Medical University, 137 Liyushan Road, Urumqi, 830011, Xinjiang, China. 208101036@csu.edu.cn.ORCID http://orcid.org/0000-0001-7970-4470

Funding

Natural Science Foundation of Xinjiang Uygur Autonomous Region 2020D01C246
6 · The paper itself

Abstract

purposeOsteoarthritis (OA) often coexists with risk factors for cardiovascular disease (CVD), worsening symptoms and functional impairment. This cross-sectional study investigated the association between Life's Essential 8 (LE8) and disability in individuals with OA.

methodsData from 8334 United States adults (aged ≥ 20) who participated in the 2005-2018 National Health and Nutrition Examination Survey (NHANES) with complete data on LE8 components and disability status were analyzed. LE8 components, including diet, physical activity (PA), nicotine exposure, sleep, body mass index (BMI), blood lipids, glucose, and blood pressure (BP), were scored on a 0-100 scale, categorizing cardiovascular health (CVH) as low, moderate, or high. Disability mainly caused by OA was assessed using a standardized physical functioning questionnaire. Association analyses were performed using multivariable logistic regression, adjusting for demographic, socioeconomic, lifestyle, and health-related covariates.

resultsIndividuals with CVH scores 10 points higher had a 15% lower prevalence of OA (95% CI 0.81-0.90). Individuals with OA were more than twice as likely to experience disability. High levels of CVH were associated with a lower prevalence of disability in various domains compared to low levels of CVH (all P < 0.05), such as in activities of daily living (OR 0.32, 95% CI 0.18-0.58). Among the LE8 components, BMI, PA, and sleep health were associated with disabilities in all domains, while blood lipid scores were not.

conclusionA higher adherence to LE8 is associated with a lower prevalence of different types of disability in domains of physical functioning and functional limitations in individuals with OA.

Indexed as

Nutrition SurveysOsteoarthritisPersons with DisabilitiesAdultAgedBody Mass IndexCross-Sectional StudiesDisability EvaluationExerciseFemaleHumansMaleMiddle AgedPrevalenceQuality of LifeRisk FactorsCardiovascular healthDisabilityLife’s Essential 8NHANESOsteoarthritis

Identifiers

PMID39167317

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.