Evidence map›Paper›PMID 39167212›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2024

The correlation of CT-derived muscle density, skeletal muscle index, and visceral adipose tissue with nutritional status in severely injured patients.

Elaine P X van Ee, Esmee A H Verheul, Suzan Dijkink, Pieta Krijnen, Wouter Veldhuis, Shirin S Feshtali, Laura Avery, Claudia J Lucassen, Sven D Mieog, John O Hwabejire and 1 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Correlation Analysis of Body Muscle-Fat Composition Parameters and CT Severity Index with Disease Severity in Acute Pancreatitis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elaine P X van EeDepartment of Trauma Surgery, Leiden University Medical Center, Post zone K6-R|, P.O. Box 9600, Leiden, 2300 RC, The Netherlands. e.p.x.van_ee@lumc.nl.
Esmee A H VerheulDepartment of Trauma Surgery, Leiden University Medical Center, Post zone K6-R|, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
Suzan DijkinkDepartment of Trauma Surgery, Leiden University Medical Center, Post zone K6-R|, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
Pieta KrijnenDepartment of Trauma Surgery, Leiden University Medical Center, Post zone K6-R|, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
Wouter VeldhuisDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Shirin S FeshtaliDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Laura AveryDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Claudia J LucassenDepartment of Dietetics, Leiden University Medical Center, Leiden, The Netherlands.
Sven D MieogDepartment of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
John O HwabejireTrauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Inger B SchipperDepartment of Trauma Surgery, Leiden University Medical Center, Post zone K6-R|, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study explored if computerized tomography-derived body composition parameters (CT-BCPs) are related to malnutrition in severely injured patients admitted to the Intensive Care Unit (ICU).

methodsThis prospective cohort study included severely injured (Injury Severity Score ≥ 16) patients, admitted to the ICU of three level-1 trauma centers between 2018 and 2022. Abdominal CT scans were retrospectively analyzed to assess the CT-BCPs: muscle density (MD), skeletal muscle index (SMI), and visceral adipose tissue (VAT). The Subjective Global Assessment was used to diagnose malnutrition at ICU admission and on day 5 of admission, and the modified Nutrition Risk in Critically ill at admission was used to assess the nutritional risk.

resultsSeven (11%) of the 65 analyzed patients had malnutrition at ICU admission, increasing to 23 patients (35%) on day 5. Thirteen (20%) patients had high nutritional risk. CT-BCPs were not related to malnutrition at ICU admission and on day 5. Patients with high nutritional risk at admission had lower MD (median (IQR) 32.1 HU (25.8-43.3) vs. 46.9 HU (37.7-53.3); p < 0.01) and higher VAT (median 166.5 cm

conclusionCT-BCPs do not seem related to malnutrition, but low MD and high VAT may be associated with high nutritional risk. These findings may prove beneficial for clinical practice, as they suggest that CT-derived parameters may provide valuable information on nutritional risk in severely injured patients, in addition to conventional nutritional assessment and screening tools. LEVEL OF EVIDENCE: Level III, Prognostic/Epidemiological.

Indexed as

Injury Severity ScoreIntensive Care UnitsIntra-Abdominal FatMalnutritionMuscle, SkeletalNutritional StatusTomography, X-Ray ComputedAdultBody CompositionFemaleHumansMaleMiddle AgedNutrition AssessmentProspective StudiesRetrospective StudiesCritical careMulticenterNutritionNutritional statusTrauma

Identifiers

PMID39167212
PMCPMC11666640

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.