Evidence map›Paper›PMID 39167189›Full record

ArticleInnere Medizin (Heidelberg, Germany)2024

[Reversibility of a critical intraventricular conduction delay under flecainide and lacosamide by sodium bicarbonate].

Anja Gallinger, Rahman Osei-Davies, F Hennersdorf

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In one paragraph

Article in Innere Medizin (Heidelberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anja GallingerKlinik für Innere Medizin, Kardiologie und Angiologie, Schön Klinik Eilbek, Dehnhaide 120, 22081, Hamburg, Deutschland. agallinger@schoen-klinik.de.
Rahman Osei-DaviesKlinik für Innere Medizin, Kardiologie und Angiologie, Schön Klinik Eilbek, Dehnhaide 120, 22081, Hamburg, Deutschland. Raosei-davies@schoen-klinik.de.
F HennersdorfKlinik für Innere Medizin, Kardiologie und Angiologie, Schön Klinik Eilbek, Dehnhaide 120, 22081, Hamburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The case of a 72-year-old female patient with arrhythmogenic syncope associated with a combination therapy of flecainide and lacosamide is presented. The authors believe in an additive effect of both drugs on myocardial voltage-gated sodium channels with extraordinary QRS widening, exit block with temporary pacing and complete reversibility through infusion of sodium bicarbonate as bail-out therapy.

Indexed as

FlecainideLacosamideSodium BicarbonateAcetamidesAgedAnti-Arrhythmia AgentsDrug Therapy, CombinationElectrocardiographyFemaleHeart Conduction SystemHumansSyncopeVoltage-Gated Sodium Channel BlockersAcetamidesAnti-Arrhythmia AgentsFlecainideLacosamideSodium BicarbonateVoltage-Gated Sodium Channel BlockersAdditive side effect of medicationsExit blockSodium channel blockersVoltage-gated sodium channelsWide QRS

Identifiers

PMID39167189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.