Evidence map›Paper›PMID 39167172›Full record

ArticleRheumatology international2024

Exploring pulmonary involvement in newly diagnosed rheumatoid arthritis, and psoriatic arthritis: a single center study.

Valentin Sebastian Schäfer, Lone Winter, Dirk Skowasch, Claus-Jürgen Bauer, Carmen Pizarro, Marcel Weber, Daniel Kütting, Charlotte Behning, Peter Brossart, Simon Michael Petzinna

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In one paragraph

Article in Rheumatology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Valentin Sebastian Schäfer *Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany.
Lone Winter *Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany.
Dirk SkowaschClinic of Internal Medicine II, Cardiology, Angiology, and Pulmonology, University Hospital Bonn, Bonn, Germany.
Claus-Jürgen BauerDepartment of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany.
Carmen PizarroClinic of Internal Medicine II, Cardiology, Angiology, and Pulmonology, University Hospital Bonn, Bonn, Germany.
Marcel WeberClinic of Internal Medicine II, Cardiology, Angiology, and Pulmonology, University Hospital Bonn, Bonn, Germany.
Daniel KüttingDepartment of Radiology, University Hospital Bonn, Bonn, Germany.
Charlotte BehningInstitute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany.
Peter BrossartDepartment of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany.
Simon Michael PetzinnaDepartment of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany. Simon_Michael.Petzinna@ukbonn.de.ORCID 0000-0002-4686-1143

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis cross-sectional study aimed to determine the prevalence, manifestation, and risk factors of pulmonary involvement in newly diagnosed, untreated rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients, and to evaluate the efficacy of various diagnostic tools in screening for pulmonary involvement.

methodsUntreated, newly diagnosed patients with RA and PsA underwent an extensive multimodal diagnostic approach including clinical and laboratory assessment, pulmonary function tests, and chest radiography.

resultsWe recruited 50 arthritis patients (26 RA, 24 PsA) and 26 control subjects. Respiratory symptoms were found in 36.0 % of arthritis patients and 11.5 % of controls (p = 0.031). Pathologically reduced breathing width (< 3.0 cm) was significantly more common in arthritis patients (64.0 %) than in controls (23.1 %) (p < 0.001). Pulmonary function test results did not differ significantly between groups. Chest radiography revealed pulmonary involvement in 37.0 % of arthritis patients, higher in RA (50.0 %) than in PsA (22.7 %). Notably, only 35.3 % of arthritis patients with radiographic pulmonary involvement were symptomatic, with 64.7 % being asymptomatic. Radiographic pulmonary involvement was associated with advanced age (p = 0.002) and increased rheumatoid factor levels (p = 0.024).

conclusionOur research underscores the significant prevalence of largely asymptomatic pulmonary involvement in newly diagnosed RA and PsA patients. These findings highlight the importance of an early, multidisciplinary screening approach, particularly for high-risk individuals. Further large-scale studies are needed to develop comprehensive screening protocols to improve early detection and treatment of pulmonary involvement in arthritis.

Indexed as

Arthritis, PsoriaticArthritis, RheumatoidRespiratory Function TestsAdultAgedCase-Control StudiesCross-Sectional StudiesFemaleHumansLungLung DiseasesMaleMiddle AgedPrevalenceRisk FactorsDiagnostics, epidemiologyExtra-articular manifestationImagingPsoriatic arthritisPulmonary involvementRheumatoid arthritis

Identifiers

PMID39167172
PMCPMC11392970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.