Evidence map›Paper›PMID 39167161›Full record

ArticleApplied microbiology and biotechnology2024

Kinetic characterization of two neuraminic acid synthases and evaluation of their application potential.

Mehmet Mervan Çakar, Nevena Milčić, Theofania Andreadaki, Simon Charnock, Wolf-Dieter Fessner, Zvjezdana Findrik Blažević

Abstract read
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In one paragraph

Article in Applied microbiology and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mehmet Mervan ÇakarUniversity of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10000, Zagreb, Croatia.ORCID http://orcid.org/0000-0001-6972-5841
Nevena MilčićUniversity of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10000, Zagreb, Croatia.ORCID http://orcid.org/0000-0003-0712-2417
Theofania AndreadakiProzomix Limited, Station Court, Haltwhistle, Northumberland, NE49 9HN, UK.
Simon CharnockProzomix Limited, Station Court, Haltwhistle, Northumberland, NE49 9HN, UK.ORCID http://orcid.org/0000-0003-4437-7419
Wolf-Dieter FessnerInstitute of Organic Chemistry and Biochemistry, Technical University of Darmstadt, Peter-Grünberg-Strasse 4, 64287, Darmstadt, Germany.ORCID http://orcid.org/0000-0002-9787-0752
Zvjezdana Findrik BlaževićUniversity of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10000, Zagreb, Croatia. zfindrik@fkit.unizg.hr.ORCID http://orcid.org/0000-0002-5312-8951

Funding

Horizon 2020 Framework Programme 956631
6 · The paper itself

Abstract

Neuraminic acid synthases are an important yet underexplored group of enzymes. Thus, in this research, we performed a detailed kinetic and stability analysis and a comparison of previously known neuraminic acid synthase from Neisseria meningitidis, and a novel enzyme, PNH

Indexed as

Enzyme StabilityNeisseria meningitidisCoenzymesHydrogen-Ion ConcentrationKineticsOxo-Acid-LyasesCoenzymesN-acetylneuraminate synthaseOxo-Acid-LyasesBiocatalysisEnzyme kineticsEnzyme stabilityNeuraminic acid synthaseSialic acids

Identifiers

PMID39167161
PMCPMC11339185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.