Evidence map›Paper›PMID 39166854›Full record

ArticleMicrobiology spectrum2024

Michael A Johnstone, William T Self

Abstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael A JohnstoneBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
William T SelfBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.ORCID 0000-0001-9874-0194

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium is a trace element that plays critical roles in redox biology; it is typically incorporated into "selenoproteins" as the 21st amino acid selenocysteine. Additionally, selenium exists as a labile non-selenocysteine cofactor in a small subset of selenoproteins known as selenium-dependent molybdenum hydroxylases (SDMHs). In purinolytic clostridia, SDMHs are implicated in the degradation of hypoxanthine, xanthine, and uric acid for carbon and nitrogen. While SDMHs have been biochemically analyzed, the genes responsible for the insertion and maturation of the selenium cofactor lack characterization. In this study, we utilized the nosocomial pathogen

Indexed as

Clostridioides difficileSeleniumUric AcidXanthineBacterial ProteinsHypoxanthineMetabolic Networks and PathwaysNutrientsPhosphotransferasesPurinesSelenoproteinsBacterial ProteinsHypoxanthineNutrientsPhosphotransferasesPurinesSeleniumselenophosphate synthetaseSelenoproteinsUric AcidXanthineClostridioides difficilemolybdoenzymepurine metabolismseleniumselenium-dependent molybdenum hydroxylaseuric acidxanthine

Identifiers

PMID39166854
PMCPMC11448449

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.