Evidence map›Paper›PMID 39166743›Full record

ArticleACS applied bio materials2024

Superhydrophobic Dressing for Singlet Oxygen Delivery in Antimicrobial Photodynamic Therapy against Multidrug-Resistant Bacterial Biofilms.

Fernanda V Cabral, QianFeng Xu, Alexander Greer, Alan M Lyons, Tayyaba Hasan

Abstract read
In one paragraph

Article in ACS applied bio materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Photodynamic anti-biofilm PHEMA/Rose Bengal hydrogels enhanced by iodide: evidence for hydrogen peroxide and triiodide formation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. AirborneAdvanced healthcare materials · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fernanda V CabralWellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, 40 Blossom Street, Boston, Massachusetts 02114, United States.ORCID 0000-0001-6247-2220
QianFeng XuSingletO2 Therapeutics LLC, VentureLink, Room 524B, 211 Warren Street, Newark, New Jersey 07103, United States.
Alexander GreerSingletO2 Therapeutics LLC, VentureLink, Room 524B, 211 Warren Street, Newark, New Jersey 07103, United States.ORCID 0000-0003-4444-9099
Alan M LyonsSingletO2 Therapeutics LLC, VentureLink, Room 524B, 211 Warren Street, Newark, New Jersey 07103, United States.ORCID 0000-0003-4410-9756
Tayyaba HasanWellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, 40 Blossom Street, Boston, Massachusetts 02114, United States.ORCID 0000-0003-0871-6057

Funding

3D-Printed Superhydrophobic-Tipped Optical Fiber for Targeted Periodontal Photodynamic TherapyR44DE026083 · NIDCR · SINGLETO2 THERAPEUTICS, LLC · PI XU, QIANFENG · 2019 to 2020
$1.5M
A Compliant Superhydrophobic Antimicrobial Photodynamic Therapy Bandage for the Prevention of Multidrug Resistant Wound InfectionsR41AI183969 · NIAID · SINGLETO2 THERAPEUTICS, LLC · PI XU, QIANFENG · 2024 to 2024
$300k
NIAID NIH HHS R41 AI183969NIDCR NIH HHS R44 DE026083
6 · The paper itself

Abstract

The rise of antimicrobial resistance poses a critical public health threat worldwide. While antimicrobial photodynamic therapy (aPDT) has demonstrated efficacy against multidrug-resistant (MDR) bacteria, its effectiveness can be limited by several factors, including the delivery of the photosensitizer (PS) to the site of interest and the development of bacterial resistance to PS uptake. There is a need for alternative methods, one of which is superhydrophobic antimicrobial photodynamic therapy (SH-aPDT), which we report here. SH-aPDT is a technique that isolates the PS on a superhydrophobic (SH) membrane, generating airborne singlet oxygen (

Indexed as

Anti-Bacterial AgentsBiofilmsDrug Resistance, Multiple, BacterialHydrophobic and Hydrophilic InteractionsMaterials TestingMicrobial Sensitivity TestsPhotochemotherapyPhotosensitizing AgentsSinglet OxygenBandagesBiocompatible MaterialsParticle SizePseudomonas aeruginosaAnti-Bacterial AgentsBiocompatible MaterialsPhotosensitizing AgentsSinglet Oxygendrug-resistant biofilmsPseudomonas aeruginosaStaphylococcus aureusverteporfinwound healing

Identifiers

PMID39166743
PMCPMC11409211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.