Evidence map›Paper›PMID 39166731›Full record

ArticleThe Laryngoscope2025

Impact of Intra-Phenotypic Nasal Vestibular Variation on Local Airflow Dynamics.

Ryan Sicard, Sarah Russel, David Jang, Ralph Abi Hachem, Dennis O Frank-Ito

Abstract read
In one paragraph

Article in The Laryngoscope, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryan SicardDepartment of Head and Neck Surgery & Communication Sciences, Duke University Medical Center, Durham, North Carolina, U.S.A.ORCID 0000-0003-1558-9893
Sarah RusselDepartment of Head and Neck Surgery & Communication Sciences, Duke University Medical Center, Durham, North Carolina, U.S.A.ORCID 0000-0001-9299-8047
David JangDepartment of Head and Neck Surgery & Communication Sciences, Duke University Medical Center, Durham, North Carolina, U.S.A.
Ralph Abi HachemDepartment of Head and Neck Surgery & Communication Sciences, Duke University Medical Center, Durham, North Carolina, U.S.A.
Dennis O Frank-ItoDepartment of Head and Neck Surgery & Communication Sciences, Duke University Medical Center, Durham, North Carolina, U.S.A.ORCID 0000-0002-9683-8355

Funding

Computational modeling of the mature unilateral cleft lip nasal deformity for objective assessment of patient nasal function and treatment outcomesR01DE028554 · NIDCR · DUKE UNIVERSITY · PI FRANK-ITO, DENNIS ONYEKA · 2019 to 2022
$1.7M
NIDCR NIH HHS R01 DE028554NIDCR NIH HHS R01DE028554
6 · The paper itself

Abstract

objectivesMany individuals with healthy normal nasal anatomy and function exhibit a prominent notch indentation at the junction of the ala and sidewall, specifically around the anterior-superior region of the unilateral nasal vestibule up to the internal nasal valve. This study evaluates the influence of various sizes of notched indentations at the anterior nasal airway on local airflow pattern.

methodsA retrospective study involving 25 healthy individuals, each exhibiting at least one unilateral notched indentation (40 total airways). Each individual's notched indentation was quantified after subject-specific three-dimensional nasal airway reconstruction from radiographic images. Computational fluid dynamics modeling was used to simulate nasal inspiratory airflow in each nasal airway at 15 L/min. Localized airflow distributions passing through the inferior, middle, and superior regions were calculated at 15 cross sections.

resultsNotched indentation size ranged 1.75-86.84 mm

conclusionsAnterior nasal airway notched indentation size had significantly stronger influence on localized airflow volume through the anterior-inferior airway than other regions of the nasal passage. LEVEL OF EVIDENCE: NA Laryngoscope, 135:50-58, 2025.

Indexed as

Nasal CavityAdultFemaleHealthy VolunteersHumansHydrodynamicsImaging, Three-DimensionalMaleMiddle AgedNosePhenotypePulmonary VentilationRetrospective StudiesYoung Adultairflowcomputational fluid dynamicsnasal vestibulenotch

Identifiers

PMID39166731
PMCPMC11637973

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.