Evidence map›Paper›PMID 39166589›Full record

ArticleJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia2024

Respiratory syncytial virus infection in children during SARS-CoV-2 pandemic at a referral center in Rio de Janeiro, Brazil.

Giuliana Pucarelli Lebreiro, Marianna Tavares Venceslau, Maria Angélica Arpon Marandino Guimarães, Thalita Fernandes Abreu, Yarina Rangel, Ana Cristina Cisne Frota, Cristina Barroso Hofer

Abstract read
In one paragraph

Article in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giuliana Pucarelli Lebreiro. Departamento de Doenças Infecciosas e Parasitárias, Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ) Brasil.ORCID http://orcid.org/0000-0002-7514-9278
Marianna Tavares Venceslau. Departamento de Doenças Infecciosas e Parasitárias, Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ) Brasil.ORCID http://orcid.org/0000-0003-0778-9297
Maria Angélica Arpon Marandino Guimarães. Departamento de Doenças Infecciosas e Parasitárias, Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ) Brasil.ORCID http://orcid.org/0000-0002-5364-7831
Thalita Fernandes Abreu. Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ) Brasil.ORCID http://orcid.org/0000-0002-6412-1093
Yarina Rangel. Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ) Brasil.ORCID http://orcid.org/0009-0006-5614-8460
Ana Cristina Cisne Frota. Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ) Brasil.ORCID http://orcid.org/0000-0002-2825-4374
Cristina Barroso Hofer. Departamento de Doenças Infecciosas e Parasitárias, Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ) Brasil.ORCID http://orcid.org/0000-0001-8633-0913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn order to study the scenario of respiratory infections in pediatrics after the emergence of SARS-CoV-2 in Brazil, this study aimed to compare characteristics of children admitted for SARS or upper airway infection caused by either RSV or SARS-CoV-2.

methodsThis was a cross-sectional study involving children up to 48 months of age admitted to a tertiary pediatric hospital with a diagnosis of SARS or upper airway infection between April of 2020 and April of 2021. Respiratory secretion samples were collected 2-5 days after hospitalization, and antigen/PCR tests for viral etiologies were performed. In this analysis, patients with laboratorial diagnosis of SARS-CoV-2 and/or RSV were selected, and their clinical and epidemiological characteristics were compared using logistic regression.

resultsOur sample initially comprised 369 participants. SARS-CoV-2 and RSV infections were confirmed in 55 (15%) and 59 children (16%), respectively. Mean age was 12 months (0-48 months), and 47 were female. The following characteristics were significantly more frequent in patients with RSV when compared with those with COVID-19: younger age (OR = 0.94; 95% CI: 0.90-0.98); lower frequency of fever (OR = 0.18; 95% CI: 0.05-0.66); and more frequent upper airway symptoms: cough (OR = 7.36; 95% CI: 1.04-52.25); and tachypnea (OR = 6.06; 95% CI: 1.31-28.0).

conclusionsChildren with RSV-related SARS were younger, had lower frequency of fever at admission, but had a higher frequency of signs of upper airway infection and lower systemic inflammation when compared with children hospitalized for COVID-19 during the first year of the pandemic.

Indexed as

COVID-19Respiratory Syncytial Virus InfectionsSARS-CoV-2BrazilChild, PreschoolCross-Sectional StudiesFemaleHospitalizationHumansInfantInfant, NewbornMalePandemics

Identifiers

PMID39166589
PMCPMC11449624

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.