Evidence map›Paper›PMID 39165857›Full record

ArticleJournal of biomedical optics2024

Optical coherence tomography otoscope for imaging of tympanic membrane and middle ear pathology.

Wihan Kim, Ryan Long, Zihan Yang, John S Oghalai, Brian E Applegate

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Imaging theJournal of biomedical optics · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wihan KimUniversity of Southern California, Caruso Department of Otolaryngology-Head & Neck Surgery, Los Angeles, California, United States.ORCID 0000-0002-4448-7215
Ryan LongUniversity of Southern California, Caruso Department of Otolaryngology-Head & Neck Surgery, Los Angeles, California, United States.ORCID 0009-0006-0448-9271
Zihan YangUniversity of Southern California, Caruso Department of Otolaryngology-Head & Neck Surgery, Los Angeles, California, United States.ORCID 0000-0003-1409-4725
John S OghalaiUniversity of Southern California, Caruso Department of Otolaryngology-Head & Neck Surgery, Los Angeles, California, United States.ORCID 0000-0003-4241-6189
Brian E ApplegateUniversity of Southern California, Caruso Department of Otolaryngology-Head & Neck Surgery, Los Angeles, California, United States.

Funding

Optical imaging technologies to identify residual cholesteatoma and improve ossiculoplasty outcomesR01EB027113 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI APPLEGATE, BRIAN E. · 2019 to 2022
$2.6M
NIBIB NIH HHS R01 EB027113
6 · The paper itself

Abstract

Significance: Pathologies within the tympanic membrane (TM) and middle ear (ME) can lead to hearing loss. Imaging tools available in the hearing clinic for diagnosis and management are limited to visual inspection using the classic otoscope. The otoscopic view is limited to the surface of the TM, especially in diseased ears where the TM is opaque. An integrated optical coherence tomography (OCT) otoscope can provide images of the interior of the TM and ME space as well as an otoscope image. This enables the clinicians to correlate the standard otoscopic view with OCT and then use the new information to improve the diagnostic accuracy and management. Aim: We aim to develop an OCT otoscope that can easily be used in the hearing clinic and demonstrate the system in the hearing clinic, identifying relevant image features of various pathologies not apparent in the standard otoscopic view. Approach: We developed a portable OCT otoscope device featuring an improved field of view and form-factor that can be operated solely by the clinician using an integrated foot pedal to control image acquisition. The device was used to image patients at a hearing clinic. Results: The field of view of the imaging system was improved to a 7.4 mm diameter, with lateral and axial resolutions of Conclusions: The developed OCT otoscope can readily fit into the hearing clinic workflow and provide new relevant information for diagnosing and managing TM and ME disease.

Indexed as

Ear, MiddleEquipment DesignOtoscopesTomography, Optical CoherenceTympanic MembraneEar DiseasesHumansOtoscopyearhearingoptical coherence tomography

Identifiers

PMID39165857
PMCPMC11334941

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.