Evidence map›Paper›PMID 39165801›Full record

ArticleProceedings (Baylor University. Medical Center)2024

The Egyptian journey from having the highest prevalence of hepatitis C virus to being the first to achieve "gold tier" in conquering the disease.

Hazem Abosheaishaa, Abdelmalek Abdelghany, Omar Abdelhalim, Islam Mohamed, Samah Morsi, Mohammed Youssef, Ahmed Salem, Ammar A Bahbah, Ahmed Shady, Mohammed S Naguib and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Proceedings (Baylor University. Medical Center), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06942962 (Assessment of Lymphocyte Subset Functions in Children Admitted to Assiut University Children Hospital With Acute Hepatitis A Infection), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06942962 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Assessment of Lymphocyte Subset Functions in Children Admitted to Assiut University Children Hospital With Acute Hepatitis A Infection

TypeobservationalSponsorAssiut UniversityRan2025 to 2026Enrolled50ConditionsHepatitis A, Hepatitis A Virus
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hazem AbosheaishaaInternal Medicine, Icahn School of Medicine at Mount Sinai, New York City Health and Hospitals, Queens Hospital Center, New York, New York, USA.ORCID https://orcid.org/0000-0002-5581-8702
Abdelmalek AbdelghanyFaculty of Medicine, October 6 University, Giza, Egypt.ORCID https://orcid.org/0009-0002-5399-1795
Omar AbdelhalimInternal Medicine, Icahn School of Medicine at Mount Sinai, New York City Health and Hospitals, Queens Hospital Center, New York, New York, USA.
Islam MohamedDepartment of Internal Medicine, University of Missouri Kansas City, Kansas City, Missouri, USA.ORCID https://orcid.org/0000-0002-0740-8960
Samah MorsiDepartment of Radiology, Mayo Clinic Rochester, Rochester, Minnesota, USA.
Mohammed YoussefDepartment of Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA.
Ahmed SalemDepartment of Medicine, Maimonides Medical Center, New York, New York, USA.ORCID https://orcid.org/0000-0001-8204-8451
Ammar A BahbahFaculty of Medicine, Menoufia University, Menoufia, Egypt.ORCID https://orcid.org/0000-0001-6150-9343
Ahmed ShadyNew York City Health and Hospitals, Metropolitan Hospital, Manhattan, New York, USA.
Mohammed S NaguibAhmed Maher Teaching Hospital, Cairo, Egypt.
Mahmoud NassarDepartment of Medicine, University at Buffalo, Buffalo, New York, USA.
Mohammed El-KassasEndemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) is a major global health concern, particularly in Egypt, due to historic schistosomiasis control efforts that inadvertently led to widespread HCV transmission. This study aimed to evaluate the efficacy of Egypt's national strategies in controlling and reducing the prevalence of HCV, including introducing sofosbuvir and implementing the "100 Million Healthy Lives" campaign. The approach includes a review of epidemiological data, an analysis of the national HCV control strategies implemented, and an assessment of their outcomes, focusing on the period from 2006 to 2022. Significant milestones were achieved, including a drastic reduction in new HCV infections from 300 per 100,000 in 2014 to 9 per 100,000 in 2022 and successful treatment of over 4 million people. Egypt has become the first country in the world to achieve the "gold tier" status based on World Health Organization criteria on the path to eradication of HCV. Egypt's comprehensive approach can serve as a model for similar endemic regions. Other nations with high HCV prevalence might benefit from adopting similar multidimensional strategies, emphasizing prevention and treatment.

Indexed as

100 Million Healthy Lives campaignDirect-acting antiviralsepidemiologyhepatitis C virussofosbuvir

Identifiers

PMID39165801
PMCPMC11332630

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.