SynthesisFrontiers in clinical diabetes and healthcare2024
A systematic review of diabetic foot infections: pathogenesis, diagnosis, and management strategies.
Synthesis in Frontiers in clinical diabetes and healthcare, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Measurement Properties of Instruments Used to Assess Diabetic Foot: An Umbrella Review.Journal of diabetes research · 2026Pooled it
- PET Micro(nano)plastics Modulate Metformin-Albumin Binding and Species-Specific Bacterial Responses.International journal of molecular sciences · 2026Article
- Indolicidin-Decorated Photosensitizer for Enhanced Antibacterials and Accelerated Diabetic Wound Healing.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Five-Year Evolution of the Microbiological Landscape of Diabetic Foot Infections (2021-2025): Rising Polymicrobial Gram-Negative Predominance and Emergence of Resistant Enterobacterales at a Single Large-Volume Outpatient Centre.Antibiotics (Basel, Switzerland) · 2026Article
- Biological and clinical significance of iron inJournal of bacteriology · 2026Review
- WGS reveals high-risk clones of Pseudomonas aeruginosa harbouring extensive antimicrobial and predicted anti-phage defense systems recovered from diabetic foot ulcer patients in Egypt.BMC microbiology · 2026Article
- A photocuring double-network hydrogel enhances mechanotransduction and scavenges ROS to accelerate pressure injury healing.Materials today. Bio · 2026Article
- Synergistic beeswax-based nano-formulation for enhanced chronic wound healing and antibacterial potency.RSC advances · 2026Article
- Population structure, antimicrobial resistance, and virulence factors of diabetic foot-associatedMicrobiology spectrum · 2026Article
- Vanillic Acid-Loaded Niosomes for Diabetic Wound Healing: Formulation, Optimization by Box-Behnken Design, and In Vivo Evaluation.AAPS PharmSciTech · 2026Article
- Comparative assessment of large language models in diabetic foot infection management: alignment with IWGDF/IDSA guidelines.Frontiers in endocrinology · 2026Article
- Integrating clinical data into evidence-based practice: institutional guideline development for diabetic foot infections.Frontiers in endocrinology · 2026Article
- Clinicopathological and microbiological profile of osteomyelitis at a teaching hospital in India: A retrospective study.Bioinformation · 2026Article
- Healing Outcomes in Diabetic Foot Ulcers Managed Within a Structured Multidisciplinary Care Model: A Retrospective Study.Journal of diabetes research · 2026Article
- Microbiological profile and antimicrobial resistance in diabetic foot infections: a cross-sectional study from a low- to middle-income country.Scientific reports · 2025Article
- Tri-layer structured intelligent hydrogel dressing for controlled-release antibacterial treatment of chronic diabetic wounds.RSC advances · 2025Article
- Antimicrobial resistance and empirical antibiotic use in diabetic foot infections: A retrospective study from Indonesia.Narra J · 2025Article
- Revolutionizing diabetic foot ulcer treatment: phage therapy as a next-generation antimicrobial approach- a review on breaking the cycle of resistance.Journal of diabetes and metabolic disorders · 2025Review
- Characterization of Microbial Profiles and Antimicrobial Resistance in Diabetic Foot Ulcers at a Tertiary Care Facility in Northern China.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Article
- From Control to Cure: Insights into the Synergy of Glycemic and Antibiotic Management in Modulating the Severity and Outcomes of Diabetic Foot Ulcers.International journal of molecular sciences · 2025Review
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Diabetic foot infection represents a significant complication of diabetes mellitus, contributing substantially to morbidity, mortality, and healthcare expenditure worldwide. Accurate diagnosis relies on a comprehensive assessment integrating clinical evaluation, imaging studies, and microbiological analysis. Management necessitates a multidisciplinary approach, encompassing surgical intervention, antimicrobial therapy, and advanced wound care strategies. Preventive measures are paramount in reducing the incidence and severity, emphasizing patient education, regular foot screenings, and early intervention. Methods: The researchers performed a systematic review of literature using PUBMED MESH keywords. Additionally, the study was registered in the International Prospective Register of Systematic Reviews at the Center for Reviews and Dissemination, University of York (CRD42021277788). This review provides a comprehensive overview of the microbial spectrum and antibiotic susceptibility patterns observed in diabetic foot infections. Results: The search through the databases finally identified 13 articles with 2545 patients from 2021 to 2023. Overall, the predominant Gram-positive microbial species isolated were Staphylococcus aureus, Enterococcus fecalis, Streptococcus pyogenes, Streptococcus agalactiae, and Staphylococcus epidermidis. Whereas the predominant Gram-negative included Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis and Pseudomonas aeruginosa. Conclusion: Diabetic foot infections represent a complex and multifaceted clinical entity, necessitating a holistic approach to diagnosis, management, and prevention. Limited high-quality research data on outcomes and the effectiveness of guideline recommendations pose challenges in updating and refining existing DFI management guidelines. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021277788, identifier CRD42021277788.
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