Evidence map›Paper›PMID 39165419›Full record

ArticleGastro hep advances2024

Decreased Abundance of Genus

Takayuki Sakai, Yu Sasaki, Yasuhiko Abe, Masakuni Shoji, Shoichi Nishise, Hidenori Sato, Makoto Yagi, Naoko Mizumoto, Yusuke Onozato, Kon Takashi and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastro hep advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Takayuki SakaiFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Yu SasakiFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Yasuhiko AbeFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Masakuni ShojiFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Shoichi NishiseTohoku Central Hospital, Yamagata, Japan.
Hidenori SatoDivision of Multi-omics Research, Yamagata University Well-Being Institute, Yamagata, Japan.
Makoto YagiFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Naoko MizumotoFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Yusuke OnozatoFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Kon TakashiFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Yuki MiyanoDivision of Multi-omics Research, Yamagata University Well-Being Institute, Yamagata, Japan.
Ryoko MurakamiDivision of Multi-omics Research, Yamagata University Well-Being Institute, Yamagata, Japan.
Matsuki UmeharaFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Shuhei NakamuraFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Minami ItoFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Takahiro WatabeFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Hiroko TsuchiyaFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Hiroki GotoFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Takahiro MiuraFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Ryo SatoFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.
Yoshiyuki UenoFaculty of Medicine, Department of Gastroenterology, Yamagata University, Yamagata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: The increasing prevalence of obesity has significantly contributed to the global burden of colorectal cancer and the precancerous colorectal adenoma (CRA). Gut microbiota vary at each stage of colorectal carcinogenesis and participate in energy homeostasis. Elucidating gut microbiotal characteristics in obesity-related CRA may help prevent and treat colorectal tumors; however, this remains unclarified. Therefore, this study investigated the gut microbiota profile of patients with obesity-related CRA. Methods: This hospital setting-based cross-sectional study included 113 participants (66 [without CRA control group] and 37 [with CRA group]; each group was divided into obese and nonobese groups) who underwent screening colonoscopy between June 2019 and January 2020. Gut microbiota were analyzed using 16S rRNA and polymerase chain reaction techniques and the data compared between the aforementioned groups. Results: No between-group difference was observed in the diversity index; however, α diversity was the lowest in the obese CRA group. The CRA group had significantly higher and lower numbers of 26 and 17 genera, respectively. Genus Conclusion: Decreased abundance of genus

Indexed as

Fecal BacteriaGut MicrobiotaPrecursor LesionVisceral Fat Accumulation

Identifiers

PMID39165419
PMCPMC11330935

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.