Evidence map›Paper›PMID 39165294›Full record

ArticleInternational journal of public health2024

A Model for Estimating the Burden of Disease of Transfusion-Transmitted Infection.

William Riley, Kailey Love, Mary Saxon, Aaron Tobian, Evan M Bloch, Ronnie Kasirye, Irene Lubega, Ezra Musisi, Aggrey Dhabangi, Dorothy Kyeyune and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

William RileyCollege of Health Solutions, Arizona State University Downtown Phoenix Campus, Phoenix, AZ, United States.
Kailey LoveCollege of Health Solutions, Arizona State University Downtown Phoenix Campus, Phoenix, AZ, United States.
Mary SaxonSandra Day O'Connor College of Law, Arizona State University, Tempe, AZ, United States.
Aaron TobianSchool of Medicine, Johns Hopkins University, Baltimore, MD, United States.
Evan M BlochSchool of Medicine, Johns Hopkins University, Baltimore, MD, United States.
Ronnie KasiryeMakerere University - Johns Hopkins University Research Collaboration, Kampala, Uganda.
Irene LubegaMakerere University - Johns Hopkins University Research Collaboration, Kampala, Uganda.
Ezra MusisiUganda Blood Transfusion Services, Kampala, Uganda.
Aggrey DhabangiMakerere University - Johns Hopkins University Research Collaboration, Kampala, Uganda.
Dorothy KyeyuneUganda Blood Transfusion Services, Kampala, Uganda.
Jeffrey McCulloughCollege of Health Solutions, Arizona State University Downtown Phoenix Campus, Phoenix, AZ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Blood transfusion is an important mode of infectious disease transmission in low- and middle-income countries (LMICs). This study describes a model to determine the prevalence of transfusion-transmitted infections (TTIs) and the associated burden of disease. Methods: A five-step model was developed to determine the TTI-related burden of disease measured by disability-adjusted life years (DALYs). Uganda was selected as the study country. Results: Approximately 298,266 units of blood were transfused in Uganda in 2019, yielding an estimated TTI incidence of 6,858 new TTIs (2.3% of transfused units) and prevalence of 19,141 TTIs (6.4% of transfused units). The total burden of disease is 2,903 DALYs, consisting of approximately 2,590 years of life lost (YLLs), and 313 years lived with disability (YLDs). Conclusion: The incidence and prevalence of TTIs and the associated burden of disease can be calculated on a local and national level. The model can be applied by health ministries to estimate the impact of TTIs in order to develop blood safety strategies to reduce the burden of disease.

Indexed as

Cost of IllnessDisability-Adjusted Life YearsTransfusion ReactionAdolescentAdultBlood-Borne InfectionsChildChild, PreschoolFemaleHumansIncidenceInfantMaleMiddle AgedPrevalenceQuality-Adjusted Life Yearsblood transfusionburden of diseasedisability adjusted life-yearstransfusion-transmitted infectionsUganda

Identifiers

PMID39165294
PMCPMC11333201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.