Evidence map›Paper›PMID 39164934›Full record

ArticleInternational journal of experimental pathology2024

Renal protective roles of macrophage matrix metalloproteinase-12 in mice with obstructed kidneys.

Shunichiro Hanai, Daiki Nakagomi, Kotaro Suzuki, Hiroshi Nakajima, Fumihiko Furuya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of experimental pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shunichiro HanaiDepartment of Rheumatology, University of Yamanashi, Yamanashi, Japan.ORCID 0000-0001-8964-8513
Daiki NakagomiDepartment of Rheumatology, University of Yamanashi, Yamanashi, Japan.
Kotaro SuzukiDepartment of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Hiroshi NakajimaDepartment of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Fumihiko FuruyaThird Department of Internal Medicine, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix metalloproteinase (MMP)-12 has been reported to have diverse functions, including regulation of immune reactions and anti-inflammatory effects, but the potential roles of MMP-12 in kidney injury have not been fully elucidated. This study aimed to determine whether MMP-12 contributes to tubulointerstitial injury in a unilateral ureteric obstruction (UUO) model. MMP-12-deficient (MMP-12

Indexed as

MacrophagesMatrix Metalloproteinase 12Mice, Inbred C57BLMice, KnockoutUreteral ObstructionAnimalsCytokinesDisease Models, AnimalFibrosisKidneyMaleMiceCytokinesmatrix metallopeptidase 12, mouseMatrix Metalloproteinase 12bone marrow‐derived macrophagefibrosisinflammationkidney diseasemacrophage elastaseresolution‐promoting factor

Identifiers

PMID39164934
PMCPMC11574677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.