ReviewHeart and vessels. Supplement1985
Eosinophilic disorders affecting the myocardium and endocardium: a review.
Review in Heart and vessels. Supplement, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 59 citations in OpenAlex.
- Neurological Manifestations of Myocarditis.Current neurology and neuroscience reports · 2022Review
- Eosinophilia With Hepatic Mass and Abnormal Liver Function Tests: An Unusual Presentation of Chronic Myeloid Leukemia.Journal of medical cases · 2020Article
- Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis.BMJ case reports · 2019Article
- Article
- Review
- Endomyocardial involvement in asymptomatic sub-Saharan immigrants with helminth-related eosinophilia.PLoS neglected tropical diseases · 2017Article
- A case report of eosinophilic myocarditis and a review of the relevant literature.BMC cardiovascular disorders · 2015Review
- From an isolated right ventricular thrombus to the diagnosis of the hypereosinophilic syndrome.Journal of cardiology cases · 2011Article
- Searching for new clues about the molecular cause of endomyocardial fibrosis by way of in silico proteomics and analytical chemistry.PloS one · 2009Article
- Clinical utility of cardiac magnetic resonance imaging in Churg-Strauss syndrome: case report and review of the literature.Rheumatology international · 2009Review
- Large apical thrombus in a patient with persistent heart failure and hypereosinophilia: Löffler endocarditis.Journal of general internal medicine · 2008Article
- Churg-Strauss syndrome and congenital factor Leiden thrombophilia as nontypical causes of intracardiac thrombosis.Heart and vessels · 2006Article
- Control of hypereosinophilic syndrome-associated recalcitrant coronary artery spasm by combined treatment with prednisone, imatinib mesylate and hydroxyurea.Experimental and clinical cardiology · 2006Article
- Cardiac involvement in Churg-Strauss syndrome shown by echocardiography.British heart journal · 1989Article
- Histopathologic and ultrastructural observations of acute and convalescent myocarditis: a serial endomyocardial biopsy study.Heart and vessels. Supplement · 1985Article
- Eosinophilic myocarditis presenting with pediatric myocardial infarction.Pediatric cardiologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A wide range of disorders give rise to eosinophil counts greater than 1.5 X 10(9)/l (hypereosinophilia) and cardiac injury. The best known of these is eosinophilic endomyocardial disease (Löffler's endomyocardial fibrosis), which occurs as a major complication of the idiopathic hypereosinophilic syndrome. Here the heart damage appears to be a direct result of tissue injury produced by toxic eosinophil granule proteins within the heart. However, it is not known what causes the eosinophilia in these patients, why the eosinophils degranulate, or why the endocardium is especially susceptible to this type of injury. A number of parasitic infections may give rise to eosinophilic myocarditis. This is usually the result of the presence of the parasites within the myocardium where they die within inflammatory lesions, which may be extensive. Occasionally, drug reactions and rejection of a transplanted heart may produce eosinophilic myocarditis. Allergic granulomatosis and vasculitis (the Churg-Strauss syndrome), which gives rise to granulomas involving the myocardium, and eosinophilic (hypersensitivity) myocarditis usually respond rapidly to treatment with steroids. However, diffuse myocardial involvement may lead to heart failure, and some of these patients may later develop dilated cardiomyopathy. It is concluded that the heart may be affected by a variety of diseases in which eosinophils are a prominent component in the inflammatory cell infiltrates. Eosinophils themselves may contribute to some of the myocardial cell injury which occurs in these diseases, and attempts to limit this with steroids may be worthwhile in some patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.