Evidence map›Paper›PMID 39164738›Full record

Observational studyJournal of health, population, and nutrition2024

Investigation of non-communicable diseases prevalence, patterns, and patient outcomes in hospitalized populations: a prospective observational study in three tertiary hospitals.

Alemu Belayneh, Legese Chelkeba, Firehiwot Amare, Henok Fisseha, Senbeta Guteta Abdissa, Mirgissa Kaba, Shivani A Patel, Mohammed K Ali

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Journal of health, population, and nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Burden of non-communicable diseases in South Asia: a decomposition analysis.Journal of health, population, and nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alemu BelaynehDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, Colleges of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0003-0039-4348
Legese ChelkebaDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, Colleges of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia. legese.chelkeba@aau.edu.et.ORCID 0000-0002-0323-5011
Firehiwot AmareDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, Colleges of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Henok FissehaDepartment of Internal Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.ORCID 0000-0002-6195-1251
Senbeta Guteta AbdissaDivision of Cardiology, Department of Internal Medicine, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0002-9378-9113
Mirgissa KabaDepartment of Community Health, School of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0002-2380-4779
Shivani A PatelHubert Department of Global Health, Rollins School of Public Health, Emory University, Georgia, Atlanta, USA.
Mohammed K AliHubert Department of Global Health, Rollins School of Public Health, Emory University, Georgia, Atlanta, USA.

Funding

COllaborative research, implementation, And LEadership training to addresS chronic Conditions across the lifecoursE (COALESCE)D43TW011404 · FIC · EMORY UNIVERSITY · PI ALI, MOHAMMED KUMAIL, HAILEMARIAM, DAMEN · 2019 to 2023
$1.2M
FIC NIH HHS D43 TW011404
6 · The paper itself

Abstract

backgroundNon-communicable diseases (NCDs) pose a significant global health challenge, constituting over 80% of mortality and morbidity. This burden is particularly pronounced in low- and middle-income countries (LMICs), including Ethiopia. Despite this, there's limited research on this issue in Africa. This study aims to investigate the prevalence, patterns, and outcomes of NCDs in hospitalized populations across three tertiary hospitals in Ethiopia.

methodsA hospital-based cohort study (August 2022 - January 2023) included patients aged 14 and older diagnosed with cardiovascular diseases (CVDs), diabetes mellitus (DM), chronic obstructive pulmonary disease (COPD), asthma, or cancer at three Ethiopian hospitals. Data on demographics, socio-economic factors, clinical characteristics, and outcomes were collected through medical records and interviews. Logistic regression identified factors independently associated with in-hospital mortality, with p ≤ 0.05 considered statistically significant.

resultsIn the study across three tertiary hospitals involving 2,237 patients, we uncovered the impact of NCDs. About 23.4% of patients struggled with NCDs, with cardiovascular diseases (53.3%), cancer (29.6%), diabetes (6.1%), and respiratory diseases (6.5%) being the most prevalent. Notably, among those affected, women comprised a slight majority (55.1%), with the average patient age being 47.2 years. Unfortunately, 15.3% of patients with NCDs faced in-hospital mortality. Our analysis revealed predictors of mortality, including cancer diagnosis (adjusted odds ratio [AOR]:1.6, 95% CI: 1.2-1.8, p = 0.01), medication adherence ( AOR: 0.36, 95% CI: 0.21-0.64, p < 0.001), concurrent infections (AOR: 0.36, 95% CI: 0.16-0.86, p < 0.001), chronic kidney diseases (CKD) (AOR: 0.35, 95% CI: 0.14-0.85, p = 0.02), and complications during hospitalization (AOR: 6.36, 95% CI: 3.45-11.71, p < 0.001).

conclusionOur study reveals a substantial prevalence of NCDs among hospitalized patients, affecting approximately one in four individuals, primarily with CVDs and cancer. Alarmingly, a significant proportion of these patients did not survive their hospitalization, emphasizing the urgent need for targeted interventions to enhance outcomes in this population.

Indexed as

HospitalizationNoncommunicable DiseasesTertiary Care CentersAdolescentAdultAgedCardiovascular DiseasesDiabetes MellitusEthiopiaFemaleHospital MortalityHumansMaleMiddle AgedNeoplasmsPrevalenceClinical outcomesHospital admissionsNon-communicable diseasesSocio-economic disparities

Identifiers

PMID39164738
PMCPMC11337899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.