Evidence map›Paper›PMID 39164723›Full record

ArticleJournal of nanobiotechnology2024

A thermo-sensitive hydrogel with prominent hemostatic effect prevents tumor recurrence via anti-anoikis-resistance.

Yang Liu, Lei Ding, Gaojie Chen, Peiyuan Wang, Xinghuan Wang

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yang LiuDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People's Republic of China.
Lei DingSchool of Rare Earths, University of Science and Technology of China, Hefei, 230026, People's Republic of China.
Gaojie ChenDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People's Republic of China.
Peiyuan WangKey Laboratory of Design and Assembly of Functional Nanostructures, Fujian Institute of Research On the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, People's Republic of China. wangpeiyuan@fjirsm.ac.cn.
Xinghuan WangDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People's Republic of China. wangxinghuan@whu.edu.cn.

Funding

Fundamental Research Funds for the Central Universities 2042022dx0003Natural Science Foundation of Fujian Province 2021J05286Natural Science Foundation of Xiamen City 3502Z202373073Program of Excellent Doctoral of Zhongnan Hospital of Wuhan University ZNYB2021018
6 · The paper itself

Abstract

Tumor cells can survive when detached from the extracellular matrix (ECM) or lose cell-cell connections, a phenomenon known as anoikis-resistance (AR). AR is closely associated with tumor cell metastasis and recurrence, enabling tumor cells to disseminate, migrate, and invade after detachment. To address this issue, a novel intervention method combining intraoperative hemostasis with multifunctional nanozyme driven-enhanced chemodynamic therapy (ECDT) has been proposed, which holds the potential to weaken the AR capability of tumor cells and suppress tumor recurrence. Here, a nanocomposite containing a dendritic mesoporous nanoframework with Cu

Indexed as

Glucose OxidaseHydrogelsAnimalsCell Line, TumorCell MovementCopperHemostasisHumansHydrogen PeroxideMiceMice, Inbred BALB CMice, NudeNanocompositesNeoplasm Recurrence, LocalPolyethylene GlycolsReactive Oxygen SpeciesCopperGlucose OxidaseHydrogelsHydrogen PeroxidePolyethylene GlycolsReactive Oxygen SpeciesAnoikis-resistanceBladder cancerEnhanced chemodynamic therapyHydrogelHypoxia inducible factor-1α

Identifiers

PMID39164723
PMCPMC11334358

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.