Evidence map›Paper›PMID 39164703›Full record

ReviewReproductive biology and endocrinology : RB&E2024

Consideration of hormonal changes for orthodontic treatment during pregnancy and lactation - a review.

Yujie Zhao, Shengqi Qian, Zhijun Zheng, Juxiang Peng, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao

Abstract readReview
In one paragraph

Review in Reproductive biology and endocrinology : RB&E, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. GDF15 modulates aging-associated adaptions in the mechanoresponse of periodontal ligament fibroblasts.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
    Article
  2. Review
  3. Article
  4. The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Review
  6. Article
  7. Dynamic changes in the pregnancy microbiome and their role in preterm birth.Frontiers in cellular and infection microbiology · 2025
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yujie ZhaoDepartment of Orthodontics, Guiyang Stomatological Hospital, No.253 Jiefang Road, Nanming District, Guiyang, Guizhou Province, 550002, China.
Shengqi QianDepartment of Stomatology, Guizhou Provincial People's Hospital, No.23 Zhongshan East Road, Nanming District, Guiyang, Guizhou Province, 550002, China.
Zhijun ZhengDepartment of Orthodontics, Guiyang Stomatological Hospital, No.253 Jiefang Road, Nanming District, Guiyang, Guizhou Province, 550002, China.
Juxiang PengDepartment of Orthodontics, Guiyang Stomatological Hospital, No.253 Jiefang Road, Nanming District, Guiyang, Guizhou Province, 550002, China.
Jianguo LiuOral Disease Research Key Laboratory of Guizhou Tertiary Institution, School of Stomatology, Zunyi Medical University, Zunyi, 563006, China.
Xiaoyan GuanDepartment of Orthodontics II, Affiliated Stomatological Hospital of Zunyi Medical University, No.143 Dalian Road, Huichuan District, Zunyi, Guizhou Province, 563000, China. 1278279125@qq.com.
Chengcheng LiaoDepartment of Orthodontics II, Affiliated Stomatological Hospital of Zunyi Medical University, No.143 Dalian Road, Huichuan District, Zunyi, Guizhou Province, 563000, China. lcc_950330@163.com.

Funding

Construction Project of Medical Biomaterials R&D Talent Base of Guizhou Province RCJD2018-9the Guizhou Provincial Health Commission Science and Technology Fund Project 2024GZWJKJXM0828the Project to Cultivate Young Scientific and Technological Talents in Colleges and Universities of Guizhou Province Zun Shi Ke He HZ Zi (2022) No. 423the Science and Technology Plan Project of Guiyang Municipal Health Bureau ZhuWeijian Technology [2022] -019the Zunyi Science and Technology Bureau and Zunyi Medical University Science and Technology Joint Fund QianShiKeHe HZ Zi (2022) No.393
6 · The paper itself

Abstract

Hormonal changes in pregnant and lactating women significantly affect bone metabolism and overall stress levels, positioning them as a unique group within the orthodontic population. Fluctuations in estrogen, progesterone, prolactin, and other hormones are closely linked to bone remodeling and the periodontal tissue's response to inflammation caused by dental plaque. Hormones such as thyrotropin, leptin, and melatonin also play crucial roles in pregnancy and bone remodeling, with potential implications for orthodontic tooth movement. Additionally, adverse personal behaviors and changes in dietary habits worsen periodontal conditions and complicate periodontal maintenance during orthodontic treatment. Notably, applying orthodontic force during pregnancy and lactation may trigger stress responses in the endocrine system, altering hormone levels. However, these changes do not appear to adversely affect the mother or fetus. This review comprehensively examines the interaction between hormone levels and orthodontic tooth movement in pregnant and lactating women, offering insights to guide clinical practice.

Indexed as

LactationBone RemodelingFemaleHormonesHumansPregnancyTooth Movement TechniquesHormonesBone remodelingHormoneLactationOrthodonticPregnancy

Identifiers

PMID39164703
PMCPMC11334371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.