Evidence map›Paper›PMID 39164546›Full record

ArticleActa parasitologica2024

First Molecular Evidence of Leishmania Infantum in Domestic Cats and Associated Risk Factors from the Black Sea Region of Türkiye.

Didem Pekmezci, Alparslan Yildirim, Zeynep Nurselin Kot, Gamze Nur Konacoglu, Onder Duzlu, Gamze Yetismis, Sadullah Uslu, Seray Toz, Yusuf Ozbel, Abdullah Inci and 1 more

Abstract read
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In one paragraph

Article in Acta parasitologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Didem PekmezciDepartment of Internal Medicine, Faculty of Veterinary Medicine, University of Ondokuz Mayis, Samsun, Turkey. dkazanci@omu.edu.tr.ORCID http://orcid.org/0000-0003-2072-8165
Alparslan YildirimDepartment of Parasitology, Faculty of Veterinary Medicine, University of Erciyes, Kayseri, Turkey.ORCID http://orcid.org/0000-0001-9868-0363
Zeynep Nurselin KotDepartment of Internal Medicine, Faculty of Veterinary Medicine, University of Ondokuz Mayis, Samsun, Turkey.ORCID http://orcid.org/0000-0002-0631-5471
Gamze Nur KonacogluDepartment of Internal Medicine, Faculty of Veterinary Medicine, University of Ondokuz Mayis, Samsun, Turkey.ORCID http://orcid.org/0000-0002-1883-3428
Onder DuzluDepartment of Parasitology, Faculty of Veterinary Medicine, University of Erciyes, Kayseri, Turkey.ORCID http://orcid.org/0000-0002-6951-0901
Gamze YetismisDepartment of Parasitology, Faculty of Veterinary Medicine, University of Erciyes, Kayseri, Turkey.ORCID http://orcid.org/0000-0001-5260-3450
Sadullah UsluDepartment of Parasitology, Faculty of Veterinary Medicine, University of Erciyes, Kayseri, Turkey.ORCID http://orcid.org/0000-0003-3445-3000
Seray TozDepartment of Parasitology, Faculty of Medicine, University of Ege, Izmir, Turkey.ORCID http://orcid.org/0000-0001-5957-8665
Yusuf OzbelDepartment of Parasitology, Faculty of Medicine, University of Ege, Izmir, Turkey.ORCID http://orcid.org/0000-0001-8335-1997
Abdullah InciDepartment of Parasitology, Faculty of Veterinary Medicine, University of Erciyes, Kayseri, Turkey.ORCID http://orcid.org/0000-0003-1614-0756
Gokmen Zafer PekmezciPreclinical Sciences, Faculty of Veterinary Medicine, University of Ondokuz Mayis, Samsun, Turkey.ORCID http://orcid.org/0000-0002-7791-1959

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objectives of the present study are to determine the molecular prevalence of Leishmania spp. in the owned domestic cats in the Black Sea Region of Türkiye and analyze the associated risk factors in FeL.

methodsConjunctival swabs (CS), blood, demographic, and clinical data were collected from 150 owned cats brought to the Veterinary Teaching Hospital during 2020-2022. Leishmania kinetoplast DNA (kDNA) from CS was screened by TaqMan Real-Time PCR (qPCR) with the genus-specific primers and a probe.

resultsAll qPCR positive products were also amplified and sequenced to identify Leishmania species by ITS1 primers. Molecular prevalence of L. infantum found as 12.6% (19/150) in the observed cats in the Black Sea Region of Türkiye. There was a significant difference (p < 0.05) between neutered and intact cats with regarding to L. infantum positivity. Intact cats found to be 0.368 times more prone to be L. infantum-positive (L+). Dermatological lesions were found the most common (26.3%) problems in the L + cats. The median leucocyte count was the only parameter that was found statistically (p < 0.05) lower in the L + group (6.60) than the negative group (L-) (8.96), when comparing the WBC, NEU/LYM, MONO/LYM, EOS/LYM and PLT/LYM values.

conclusionThis study presented the molecular occurrence of FeL in the Black Sea Region of Türkiye for the first time indicating that the carrier status of the cats makes them alternative reservoirs for possible zoonotic transmission of L. infantum in this zone.

Indexed as

Cat DiseasesLeishmania infantumAnimalsBlack SeaCatsDNA, KinetoplastDNA, ProtozoanFemaleLeishmaniasis, VisceralMalePrevalenceReal-Time Polymerase Chain ReactionRisk FactorsDNA, KinetoplastDNA, ProtozoanConjunctival swapFeline LeishmaniosisLeishmania InfantumqPCRRisk FactorsTürkiye

Identifiers

PMID39164546

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.