ArticleNature immunology2024
Influenza vaccination stimulates maturation of the human T follicular helper cell response.
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Article in Nature immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- Trial
- Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026Review
- The Role of CD4 T Cell Repertoire and Immune Memory Mechanisms in Vaccination and Infection Immunity.Immunological reviews · 2026Review
- Post-vaccination expansion of extrafollicular Th10 and regulatory Tfr cells distinguishes strong from weak influenza vaccine responses in older adults.medRxiv : the preprint server for health sciences · 2026Article
- Circulating T-follicular helper and type I regulatory T cells have overlapping phenotypes inbioRxiv : the preprint server for biology · 2026Article
- Local B cell immunity and durable memory after live-attenuated influenza intranasal vaccination of humans.Science translational medicine · 2026Article
- Comparison of CD4 T-Cell Response in Plasmodium falciparum and vivax Malaria.The Journal of infectious diseases · 2026Article
- Antiviral CD4Communications medicine · 2026Article
- Immunological memory to vaccines.Immunity · 2026Review
- Aging restricts maturation of CXCL13bioRxiv : the preprint server for biology · 2026Article
- Divergent phenotypic and functional roles of human T follicular helper cells from infancy to adulthood.bioRxiv : the preprint server for biology · 2026Article
- Comparative analysis of cellular immune responses to four seasonal inactivated influenza vaccines in younger and older adults.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Multimodal analysis definesbioRxiv : the preprint server for biology · 2025Article
- Article
- Establishing long-lasting vaccine immunity: insights from mRNA and adjuvanted protein platforms.NPJ vaccines · 2025Review
- Tfh2 and a subset of Tfh1 cells associate with antibody-mediated immunity to malaria.JCI insight · 2025Article
- Pneumococcal vaccine hyporesponsiveness in people living with HIV: A narrative review of immunological mechanisms and insights from minimally invasive lymph node sampling.Human vaccines & immunotherapeutics · 2025Review
- Early lymph node T follicular helper cell signalling hub drives influenza vaccine response in an ancestrally diverse cohort.EBioMedicine · 2025Article
- Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity.Nature immunology · 2025Article
- IFITM3-deficient mice as a model for testing influenza virus vaccines via the intramuscular route.Vaccine · 2025Article
Corrections and comments
- Update of
Authors and funding
19 authors.
Stefan A Schattgen *Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-6860-5079
Jackson S Turner *Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-4396-6265
Mohamed A Ghonim *Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jeremy Chase CrawfordDepartment of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0003-4096-6048
Aaron J SchmitzDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Hyunjin KimDepartment of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA.
Julian Q ZhouDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0001-9602-2092
Walid AwadDepartment of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA.
Robert C MettelmanDepartment of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-3527-5616
Wooseob KimDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Katherine M McIntireDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Alem HaileClinical Trials Unit, Washington University School of Medicine, St. Louis, MO, USA.
Michael K KlebertClinical Trials Unit, Washington University School of Medicine, St. Louis, MO, USA.
Teresa SuessenMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
William D MiddletonMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Sharlene A TeefeyMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Rachel M PrestiDivision of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Ali H EllebedyDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. ellebedy@wustl.edu.ORCID http://orcid.org/0000-0002-6129-2532
Paul G ThomasDepartment of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA. paul.thomas@stjude.org.ORCID http://orcid.org/0000-0001-7955-0256
Funding
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00016 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI WEBBY, RICHARD · 2021 to 2025
$91.4MCOVID Supplement - COMPONENT A OF THE COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTERS (CIVICS) PROGRAM TO DESIGN AND EVALUATE INNOVATIVE INFLUENZA VACCINE APPROACHES,75N93019C00052 · NIAID · UNIVERSITY OF GEORGIA · PI ROSS, TED · 2019 to 2025
$74.6MHousehold Respiratory Virus SARS-CoV-2 Transmission and Immunity Sub-Study (HRTS)U01AI144616 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI GORDON, AUBREE L, THOMAS, PAUL G. · 2019 to 2025
$43.7MDECODING THE INTERACTIONS BETWEEN T CELL RECEPTORS AND PEPTIDE-MHCR01AI136514 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Paul G. Thomas · 2018 to 2026
$6.9MDYNAMICS AND EVOLUTION OF IMMUNE RESPONSES TO INFLUENZA VIRUSESU01AI150747 · NIAID · EMORY UNIVERSITY · PI AHMED, RAFI, ANTIA, RUSTOM NOSHIR · 2020 to 2024
$5.9MProgramming Durable Immune Responses To VaccinationU01AI141990 · NIAID · WASHINGTON UNIVERSITY · PI Ali Hassan Ellebedy · 2019 to 2026
$5.3MDIVISION OF LABOR IN HUMAN B CELL RESPONSES TO INFLUENZA VIRUSESR21AI139813 · NIAID · WASHINGTON UNIVERSITY · PI ELLEBEDY, ALI HASSAN · 2018 to 2019
$419kInvestigating the cellular responses to influenza virus infection and the origins of first exposure immune imprintingF32AI157296 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI METTELMAN, ROBERT C · 2021 to 2023
$210kNIAID NIH HHS 75N93019C00052NIAID NIH HHS 75N93021C00016NIAID NIH HHS F32 AI157296NIAID NIH HHS HHSN272201400006CNIAID NIH HHS R01 AI136514NIAID NIH HHS R21 AI139813NIAID NIH HHS U01 AI141990NIAID NIH HHS U01 AI144616NIAID NIH HHS U01 AI150747U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) F32AI157296U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI136514U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U01AI144616
Abstract
The differentiation and specificity of human CD4
Indexed as
Cell DifferentiationGerminal CenterInfluenza, HumanInfluenza VaccinesT Follicular Helper CellsVaccinationAdultFemaleHumansImmunologic MemoryInterleukin-10Lymph NodesMaleMiddle AgedT-Lymphocytes, Helper-InducerYoung AdultInfluenza VaccinesInterleukin-10
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.