ArticleAbdominal radiology (New York)2025
Diagnostic performance of a modified O-RADS classification system for adnexal lesions incorporating clinical features.
Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Performance of MRI protocols for diagnosis of benign and malignant ovarian tumors: a systematic review and meta-analysis.Abdominal radiology (New York) · 2026Pooled it
- Multimodal Deep Learning Based on Ultrasound Images and Clinical Data for Better Ovarian Cancer Diagnosis.Journal of imaging informatics in medicine · 2026Article
- Article
- Diagnostic value of multiparametric MRI combined with an interpretable machine learning model in the differentiation of benign and malignant ovarian-adnexal lesions classified as O-RADS 4.BMC medical imaging · 2025Article
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10 authors.
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Abstract
purposeTo compare the diagnostic efficacy of the Ovarian-Adnexal Reporting and Data System (O-RADS) MRI score with that of the modified O-RADS score on the basis of a simplified contrast-enhanced (CE) MRI protocol in characterizing adnexal masses with solid tissue. The added value of clinical features was evaluated to improve the ability of the scoring system to classify adnexal masses.
methodsA total of 124 patients with 124 adnexal lesions containing solid tissue were included in this two-center retrospective study. Among them, there were 40 benign lesions (40/124, 32.3%) and 84 were malignant lesions (84/124, 67.7%). Three radiologists independently reviewed the images and assigned the O-RADS MRI score and the modified O-RADS score for each adnexal mass. Histopathology was used as the reference standard. The diagnostic efficacy of the two scoring methods was compared. Univariate and multivariate logistic regression were performed to evaluate the value of significant features in the prediction of malignant tumors.
resultsThe O-RADS MRI score and modified O-RADS score showed sensitivity at 100.0% (95% CI, 95.7-100.0%) and 71.4% (95% CI, 60.5-80.8%), specificity at 12.5% (95% CI, 4.2-26.8%) and 75.0% (95% CI, 58.8-87.3%), respectively. The area under the curve of the modified O-RADS score was higher than the O-RADS score (0.732 [95% CI, 0.645-0.808] vs 0.575 [95% CI, 0.483-0.663]; p < 0.001). Multivariate analysis showed that the modified O-RADS score 4b or 5 combined with patient age > 38.5 years, nullipara, maximum diameter > 40.5 mm and HE4 > 78.9 pmol/L significantly improved the diagnostic efficacy up to 0.954 (95% CI, 0.901-0.984) (p < 0.001).
conclusionA modified O-RADS score combined with certain clinical features can significantly improve the diagnostic efficacy in predicting malignant tumors.
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