Evidence map›Paper›PMID 39164453›Full record

ArticleJournal of imaging informatics in medicine2025

Lesion Classification by Model-Based Feature Extraction: A Differential Affine Invariant Model of Soft Tissue Elasticity in CT Images.

Weiguo Cao, Marc J Pomeroy, Zhengrong Liang, Yongfeng Gao, Yongyi Shi, Jiaxing Tan, Fangfang Han, Jing Wang, Jianhua Ma, Hongbin Lu and 2 more

Abstract read
In one paragraph

Article in Journal of imaging informatics in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Weiguo CaoDepartment of Radiology, Stony Brook University, Stony Brook, NY, 11794, USA. george.wg.cao@gmail.com.ORCID http://orcid.org/0000-0001-9181-6133
Marc J PomeroyDepartment of Radiology, Stony Brook University, Stony Brook, NY, 11794, USA.
Zhengrong LiangDepartment of Radiology, Stony Brook University, Stony Brook, NY, 11794, USA. jerome.liang@stonybrook.edu.
Yongfeng GaoDepartment of Radiology, Stony Brook University, Stony Brook, NY, 11794, USA.
Yongyi ShiDepartment of Radiology, Stony Brook University, Stony Brook, NY, 11794, USA.
Jiaxing TanDepartment of Computer Science, City University of New York, New York, NY, 10314, USA.
Fangfang HanSchool of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong, China.
Jing WangDepartment of Radiation Oncology, University of Texas Southwestern Medical Centre, Dallas, TX, 75235, USA.
Jianhua MaDepartment of Radiation Oncology, University of Texas Southwestern Medical Centre, Dallas, TX, 75235, USA.
Hongbin LuDepartment of Biomedical Engineering, The Fourth Medical University, Xi'an, China.
Almas F AbbasiDepartment of Radiology, Stony Brook University, Stony Brook, NY, 11794, USA.
Perry J PickhardtDepartment of Radiology, School of Medicine, University of Wisconsin, Madison, WI, 53792, USA.

Funding

(PQ6) Radiogenomics of colorectal polyps to assess benign proliferative vs. premalignant states.R01CA220004 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GRADY, WILLIAM MALLORY, HALBERG, RICHARD BROTT · 2017 to 2021
$3.2M
Advancing Virtual Colonoscopy for Early Cancer ScreeningR01CA206171 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI LIANG, JEROME Z · 2016 to 2020
$2.0M
NCI NIH HHS R01 CA206171NCI NIH HHS R01 CA220004NIH/NCI CA206171NIH/NCI CA220004
6 · The paper itself

Abstract

The elasticity of soft tissues has been widely considered a characteristic property for differentiation of healthy and lesions and, therefore, motivated the development of several elasticity imaging modalities, for example, ultrasound elastography, magnetic resonance elastography, and optical coherence elastography to directly measure the tissue elasticity. This paper proposes an alternative approach of modeling the elasticity for prior knowledge-based extraction of tissue elastic characteristic features for machine learning (ML) lesion classification using computed tomography (CT) imaging modality. The model describes a dynamic non-rigid (or elastic) soft tissue deformation in differential manifold to mimic the tissues' elasticity under wave fluctuation in vivo. Based on the model, a local deformation invariant is formulated using the 1

Indexed as

Colonic PolypsElasticity Imaging TechniquesLung NeoplasmsRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedAlgorithmsHumansMachine LearningReproducibility of ResultsSensitivity and SpecificityAffine transformationElastic deformationInvariant characteristicsLesion classificationTissue elasticity

Identifiers

PMID39164453
PMCPMC11950485

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.