Evidence map›Paper›PMID 39164295›Full record

ArticleScientific reports2024

Deferoxamine preconditioning of canine stem cell derived extracellular vesicles alleviates inflammation in an EAE mouse model through STAT3 regulation.

Su-Min Park, Yong-Hun Oh, Ga-Hyun Lim, Ga-Hee Yun, Kyung-Bo Kim, Ju-Hyun An, Kyung-Won Seo, Hwa-Young Youn

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Su-Min ParkLaboratory of Veterinary Internal Medicine and Research Institute for Veterinary Science, Department of Clinical Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Yong-Hun OhLaboratory of Veterinary Internal Medicine and Research Institute for Veterinary Science, Department of Clinical Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Ga-Hyun LimLaboratory of Veterinary Internal Medicine and Research Institute for Veterinary Science, Department of Clinical Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Ga-Hee YunLaboratory of Veterinary Internal Medicine and Research Institute for Veterinary Science, Department of Clinical Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Kyung-Bo KimLaboratory of Veterinary Internal Medicine and Research Institute for Veterinary Science, Department of Clinical Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Ju-Hyun AnDepartment of Veterinary Emergency and Critical Care Medicine and Institute of Veterinary Science, College of Veterinary Medicine, Kangwon National University, Chuncheon-si, Republic of Korea.
Kyung-Won SeoLaboratory of Veterinary Internal Medicine and Research Institute for Veterinary Science, Department of Clinical Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Hwa-Young YounLaboratory of Veterinary Internal Medicine and Research Institute for Veterinary Science, Department of Clinical Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea. hyyoun@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) from mesenchymal stem cells (MSCs), specifically those preconditioned with deferoxamine (DFO) in canine adipose tissue-derived MSCs (cAT-MSCs), were explored for treating autoimmune diseases. This study assessed the effects of DFO-preconditioned EVs (EV

Indexed as

DeferoxamineEncephalomyelitis, Autoimmune, ExperimentalExtracellular VesiclesInflammationMesenchymal Stem CellsSTAT3 Transcription FactorT-Lymphocytes, RegulatoryAnimalsDisease Models, AnimalDogsFemaleMiceDeferoxamineStat3 protein, mouseSTAT3 Transcription FactorDeferoxamineExperimental autoimmune encephalomyelitisExtracellular vesiclesImmune modulationMesenchymal stem cellsSTAT3

Identifiers

PMID39164295
PMCPMC11335858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.