Evidence map›Paper›PMID 39163102›Full record

SynthesisJMIR dermatology2024

Association of Cellulitis With Obesity: Systematic Review and Meta-Analysis.

Kimi Gabriella Taira, Madelyn Wang, William Guo, Olivia Kam, Tara Kaufmann

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in JMIR dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kimi Gabriella Taira *Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, United States.ORCID 0009-0007-0067-694X
Madelyn Wang *Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, United States.ORCID 0000-0001-7576-1179
William GuoDepartment of Dermatology, Stony Brook University Hospital, Stony Brook, NY, United States.ORCID 0000-0003-1867-7653
Olivia KamRenaissance School of Medicine, Stony Brook University, Stony Brook, NY, United States.ORCID 0000-0003-0034-5992
Tara KaufmannDepartment of Dermatology, Stony Brook University Hospital, Stony Brook, NY, United States.ORCID 0009-0005-1528-0951

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCellulitis is a bacterial skin infection that tends to recur. Previous studies have identified several risk factors that may contribute to its pathogenesis. Obesity is an increasingly prevalent worldwide disease that has been associated with skin and soft tissue infections.

objectiveThe aim of our systematic review and meta-analysis was to investigate the association of cellulitis with obesity.

methodsThe Ovid MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and Web of Science databases were searched for the relevant studies from the inception of each respective database to March 13, 2021. Case-control, cross-sectional, or cohort studies that examined the odds or risk of increased BMI in patients with cellulitis were included. This study was carried out in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The Newcastle-Ottawa scale (NOS) was used to evaluate the risk of bias in included studies.

resultsIn total, 9 case-control studies were included in our quantitative meta-analysis with a total of 68,148 study participants. A significant association was found between cellulitis and obesity (pooled odds ratio [OR] 2.67, 95% CI 1.91-3.71). No significant association was observed between cellulitis and being overweight (pooled OR 1.69, 95% CI 0.99-2.88). Patients with cellulitis were also found to have 1.63-fold increased odds of being male (pooled OR 1.63, 95% CI 1.12-2.38).

conclusionsOur findings suggest that cellulitis is significantly associated with obesity. Maintaining a healthy BMI may be indicated for patients presenting with cellulitis.

Indexed as

CellulitisObesityBody Mass IndexCase-Control StudiesHumansRisk FactorsBMIbody mass indexcellulitismeta-analysisobesityoverweightskin infectionsystematic review

Identifiers

PMID39163102
PMCPMC11372331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.