Evidence map›Paper›PMID 39162944›Full record

ReviewReviews in endocrine & metabolic disorders2024

Primary hyperparathyroidism: from guidelines to outpatient clinic.

Andrea Palermo, Gaia Tabacco, Polyzois Makras, Guido Zavatta, Pierpaolo Trimboli, Elena Castellano, Maria P Yavropoulou, Anda Mihaela Naciu, Athanasios D Anastasilakis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. [Coagulation function analysis and postoperative changes in patients with primary hyperparathyroidism].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Is theLangenbeck's archives of surgery · 2025
    Observational
  16. Article
  17. Review
  18. Review
  19. Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrea PalermoUnit of Metabolic Bone and Thyroid Disorders, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome, 00128, Italy. a.palermo@unicampus.it.ORCID 0000-0002-1143-4926
Gaia TabaccoUnit of Metabolic Bone and Thyroid Disorders, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome, 00128, Italy.ORCID 0000-0002-6808-0700
Polyzois MakrasDivision of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0002-3231-3357
Guido ZavattaDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Via Massarenti 9, Bologna, 40138, Italy.ORCID 0000-0003-3657-2070
Pierpaolo TrimboliFacoltà di Scienze Biomediche, Università della Svizzera Italiana (USI), Lugano, 6900, Switzerland.ORCID 0000-0002-2125-4937
Elena CastellanoEndocrinology Unit, First Department of Propaedeutic and Internal Medicine, Medical School, National and Kapodistrian University of Athens, Athens, 11527, Greece.ORCID 0000-0001-6622-4267
Maria P YavropoulouDepartment of Endocrinology, 424 Military General Hospital, Thessaloniki, Greece.ORCID 0000-0002-6501-3692
Anda Mihaela NaciuUnit of Metabolic Bone and Thyroid Disorders, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome, 00128, Italy.ORCID 0000-0002-4576-3381
Athanasios D AnastasilakisDepartment of Endocrinology, 424 Military General Hospital, Thessaloniki, Greece.ORCID 0000-0002-9624-6296

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary hyperparathyroidism (PHPT) is a common endocrine disease characterized by hypercalcemia due to inappropriately high parathyroid hormone secretion. While in the typical, symptomatic form of the disease diagnosis is set easily and standard management is surgical removal of the hyperfunctioning parathyroid (HP), this may not be the case in more subtle forms of PHPT, such as the asymptomatic and the normocalcemic PHPT. Localization of the HP could also be challenging, especially in small-sized adenomas, ectopic lesions or multiglandular disease. An experienced surgical team is essential to achieve curative parathyroidectomy. In this article, we used illustrative clinical vignettes to dissect the approach to the patient with PHPT, from the diagnosis establishment to the suggested investigation to identify classical and non-classical PHPT features and the methodology to locate the abnormal tissue. Accordingly, we elaborated on appropriate management, both surgical and conservative.

Indexed as

Hyperparathyroidism, PrimaryAmbulatory Care FacilitiesFemaleHumansMaleMiddle AgedParathyroidectomyPractice Guidelines as TopicCalciumParathyroid glandPrimary hyperparathyroidismPTH

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.