Evidence map›Paper›PMID 39162901›Full record

ArticleEJNMMI radiopharmacy and chemistry2024

Radiosynthesis and preclinical evaluation of a

Piyapan Suwattananuruk, Sukanya Yaset, Chanisa Chotipanich, Angel Moldes-Anaya, Rune Sundset, Rodrigo Berzaghi, Stine Figenschau, Sandra Claes, Dominique Schols, Pornchai Rojsitthisak and 2 more

Abstract read
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. CXCR4-targeted PET imaging of glioblastoma using [EJNMMI radiopharmacy and chemistry · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Piyapan SuwattananurukDepartment of Food and Pharmaceutical Chemistry and Center of Excellence in Natural Products for Ageing and Chronic Diseases, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Sukanya YasetNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, Thailand.
Chanisa ChotipanichNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, Thailand.
Angel Moldes-AnayaPET Imaging Center, University Hospital of North Norway, Tromsø, Norway.
Rune SundsetPET Imaging Center, University Hospital of North Norway, Tromsø, Norway.
Rodrigo BerzaghiDepartment of Clinical Medicine, Nuclear Medicine and Radiation Biology Research Group, UiT The Arctic University of Norway, Tromsø, Norway.
Stine FigenschauDepartment of Clinical Medicine, Nuclear Medicine and Radiation Biology Research Group, UiT The Arctic University of Norway, Tromsø, Norway.
Sandra ClaesDepartment of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, KU Leuven, Louvain, Belgium.
Dominique ScholsDepartment of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, KU Leuven, Louvain, Belgium.
Pornchai RojsitthisakDepartment of Food and Pharmaceutical Chemistry and Center of Excellence in Natural Products for Ageing and Chronic Diseases, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Mathias Kranz *PET Imaging Center, University Hospital of North Norway, Tromsø, Norway. mathias.kranz@uit.no.ORCID https://orcid.org/0000-0002-5641-7396
Opa Vajragupta *Department of Food and Pharmaceutical Chemistry and Center of Excellence in Natural Products for Ageing and Chronic Diseases, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand. Opa.V@chula.ac.th.ORCID http://orcid.org/0000-0003-3313-0621

Funding

Graduate School, Chulalongkorn University 100th Anniversary Chulalongkorn University Fund for Doctoral ScholarshipGraduate School, Chulalongkorn University 90th Anniversary of Chulalongkorn University Scholarship (GCUGR1125652013D)National Research Council of Thailand The National Research Council of Thailand (NRCT) under Molecular Probes for Imaging International Research Network (IRN N10A650046) (O.V.)Trond Mohn Foundation (TMF) and Helse-Nord grant Helse-Nord grant HNF1591-21/HNF1695-23Trond Mohn Foundation (TMF) and Helse-Nord grant Trond Mohn Foundation (TMF)
6 · The paper itself

Abstract

backgroundThis study aimed to develop a novel positron emission tomography (PET) tracer, [

methodsA bifunctional chelator was prepared by conjugating the amine group of TIQ15 with p-NCS-Bz-DOTA, yielding TD-01, with a high yield (68.92%). TD-01 was then radiolabeled with

results[

conclusionThe newly developed CXCR4 PET tracer, [

Indexed as

68GaBifunctional chelator (BFC)CXCR4 receptorGlioblastoma (GBM)PET tracerPositron emission tomography

Identifiers

PMID39162901
PMCPMC11335985

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.