Evidence map›Paper›PMID 39162868›Full record

Trial reportBrain topography2024

Repetitive Transcranial Magnetic Stimulation with Body Weight-supported Treadmill Training Enhances Independent Walking of Individuals with Chronic Incomplete Spinal Cord Injury: A Pilot Randomized Clinical Trial.

Fernanda Nogueira, Lívia Shirahige, Rodrigo Brito, Hamably Lima, João Victor, María Paz Sanchez, Jocemar Ilha, Katia Monte-Silva

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Brain topography, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fernanda NogueiraApplied Neuroscience Laboratory, Department of Physical Therapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, 173-, Recife, CEP 50670-901, Pernambuco, Brazil.
Lívia ShirahigeApplied Neuroscience Laboratory, Department of Physical Therapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, 173-, Recife, CEP 50670-901, Pernambuco, Brazil.
Rodrigo BritoApplied Neuroscience Laboratory, Department of Physical Therapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, 173-, Recife, CEP 50670-901, Pernambuco, Brazil.
Hamably LimaApplied Neuroscience Laboratory, Department of Physical Therapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, 173-, Recife, CEP 50670-901, Pernambuco, Brazil.
João VictorApplied Neuroscience Laboratory, Department of Physical Therapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, 173-, Recife, CEP 50670-901, Pernambuco, Brazil.
María Paz SanchezApplied Neuroscience Laboratory, Department of Physical Therapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, 173-, Recife, CEP 50670-901, Pernambuco, Brazil.
Jocemar IlhaDepartment of Fisioterapia, Universidade do Estado de Santa Catarina, Rua Pascoal Simone, 358, Florianópolis, CEP 88080-350, SC, Brazil.
Katia Monte-SilvaApplied Neuroscience Laboratory, Department of Physical Therapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, 173-, Recife, CEP 50670-901, Pernambuco, Brazil. monte.silva@ufpe.br.

Funding

CNPq/Brazil 311224/2019-9
6 · The paper itself

Abstract

The purpose of this study is to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with body weight-support treadmill training (BWSTT) for improving walking function of individuals with chronic incomplete spinal cord injury (iSCI). A 4-week, double-blinded, randomized, sham-controlled pilot study involved 12 sessions of real (10 Hz, 1800 pulses) or sham rTMS combined with BWSTT (15-20 min, moderate intensity). Walking independence was assessed using the Walking Index for Spinal Cord Injury II (WISCI-II). Lower extremity motor function (lower extremity motor score [LEMS]) and spasticity, sensory function, functional independence (Spinal Cord Injury Measure III [SCIM-III]), and quality of life were also assessed. Walking independence (WISCI-II) after the 6th session was higher in the BWSTT/rTMS real (n = 7) (median change (IQR): 3 (1.5 to 3.5)) than in the sham group (n = 8) (median change (IQR): 0 (0 to 0.25), but there was no difference between groups after 12th session (BWSTT/rTMS real median change (IQR): 4 (2 to 5); BWSSTT/rTMS sham median change (IQR): 0 (0 to 3.25). Compared to baseline, LEMS and SCIM-III mobility scores were increased after 12 sessions in the BWSTT/rTMS real but not in the sham group. Within- and between-group sensory function, functional independence, and quality of life remained similar. This preliminary result suggests that combining BWSTT with rTMS could lead to earlier gait improvement in patients with chronic iSCI.

Indexed as

Exercise TherapySpinal Cord InjuriesTranscranial Magnetic StimulationWalkingAdultBody WeightChronic DiseaseDouble-Blind MethodFemaleHumansMaleMiddle AgedPilot ProjectsQuality of LifeTreatment OutcomeBody weight-support treadmill trainingGaitRepetitive transcranial magnetic stimulationSpinal cord injury

Identifiers

PMID39162868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.