Evidence map›Paper›PMID 39162804›Full record

ArticleJournal of neurology2024

Phosphorylated tau 181 (p-tau

Maxime Bosse, Florian Bélik, Vincent van Pesch, Jean-Louis Bayart

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Article in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maxime BosseDepartment of Laboratory Medicine, Clinique Saint-Pierre, 1340, Ottignies, Belgium.ORCID http://orcid.org/0009-0005-6069-8118
Florian BélikDepartment of Laboratory Medicine, Cliniques Universitaires Saint-Luc, Brussels, Belgium.ORCID http://orcid.org/0009-0006-1564-7984
Vincent van PeschDepartment of Laboratory Medicine, Cliniques Universitaires Saint-Luc, Brussels, Belgium.ORCID http://orcid.org/0000-0003-2885-9004
Jean-Louis BayartDepartment of Laboratory Medicine, Clinique Saint-Pierre, 1340, Ottignies, Belgium. jean-louis.bayart@cspo.be.ORCID http://orcid.org/0009-0009-4802-7302

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebrospinal fluid (CSF) leaks can lead to serious complications if left untreated, making rapid and accurate diagnosis essential. Biomarkers such as β2-transferrin (B2TRF) and β-trace protein are used to detect CSF leaks, but their limitations warrant the exploration of alternative markers. This study investigates the potential of phosphorylated tau at threonine 181 (p-tau

methodsSamples from 56 subjects were analyzed for B2TRF and p-tau

resultsp-tau

conclusionsThis study highlights the potential of p-tau

Indexed as

BiomarkersCerebrospinal Fluid Leaktau ProteinsAdultAgedFemaleHumansMaleMiddle AgedPhosphorylationROC CurveSensitivity and SpecificityTransferrinBiomarkersMAPT protein, humantau ProteinsTransferrinBiomarkerCerebrospinalLeakNeurologyp-tau181

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.