Evidence map›Paper›PMID 39162778›Full record

ArticleChemistryOpen2024

Total Synthesis of Cyclosenegalin A.

Anderson Arnold Aloanis, Tati Herlina, Ari Hardianto, Rani Maharani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemistryOpen, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anderson Arnold AloanisDepartment Chemistry, Universitas Negeri Manado, Minahasa, 95619.ORCID 0000-0002-6934-1503
Tati HerlinaDepartment Chemistry, Universitas Padjadjaran, Jatinangor, 45363.
Ari HardiantoDepartment Chemistry, Universitas Padjadjaran, Jatinangor, 45363.
Rani MaharaniDepartment Chemistry, Universitas Padjadjaran, Jatinangor, 45363.ORCID 0000-0001-8156-9773

Funding

Center for Higher Education Funding (BPPT) KemendikbudristekIndonesia Endowment Fund for Education (LPDP)
6 · The paper itself

Abstract

A Pro-Gly-typed cyclopeptide, cyclosenegalin A, was firstly isolated from Annona senegalensis and Annona scleroderma. In this study, we reported synthesis the cycloheptapeptide with a combination of solid- and solution-phase synthetic methods. This study also compared the effectiveness of β-turn inducer type I and II in cyclosenegalin A to facilitate the cyclization process. The synthesis of cyclosenegalin A were prepared using two different sequences of linear peptides for cyclization. First sequence employed β-turn type I inducer (Ser-Ala-Val-Thr) as turning point and second sequence employed β-turn type II inducer (Thr-Pro-Gly-Leu). The successful cyclization was obtained using the linear sequence of NH

Indexed as

Peptides, CyclicAnti-Bacterial AgentsCyclizationMicrobial Sensitivity TestsAnti-Bacterial AgentsPeptides, CyclicBeta-turnCyclopeptideSolid-phase synthesisSolution-phase synthesisTotal synthesis

Identifiers

PMID39162778
PMCPMC12056923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.