Evidence map›Paper›PMID 39162768›Full record

ReviewVeterinary research communications2024

Endocannabinoid system and phytocannabinoids in the main species of veterinary interest: a comparative review.

Alessandra Di Salvo, Elisabetta Chiaradia, Monica Sforna, Giorgia Della Rocca

Abstract readReviewComparative Study
In one paragraph

Review in Veterinary research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alessandra Di SalvoDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.ORCID http://orcid.org/0000-0001-5934-5853
Elisabetta ChiaradiaDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy. elisabetta.chiaradia@unipg.it.ORCID http://orcid.org/0000-0002-0958-9187
Monica SfornaDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.ORCID http://orcid.org/0000-0002-7613-6540
Giorgia Della RoccaDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.ORCID http://orcid.org/0000-0002-8212-5469

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the discovery of the endocannabinoid system and due to the empirical evidence of the therapeutic effects on several illnesses both in humans and animals that follow the administration of exogenous cannabinoids (i.e., phytocannabinoids), numerous studies have been conducted. These investigations aimed to identify the expression and distribution of cannabinoid receptors in healthy and pathologic organs and tissues of different animal species and to define the interactions of phytocannabinoids with these receptors. In the last decade, pharmacokinetics, efficacy and tolerability of many Cannabis derivatives formulations, mainly containing cannabidiol, in the main species of veterinary interest, have been also investigated. This manuscript summarizes the findings reported by the scientific studies published so far on the molecular mode of action of the main phytocannabinoids, the localization of cannabinoid receptors in organs and tissues, as well as the pharmacokinetics, efficacy and tolerability of Cannabis derivatives in dogs, cats, horses and other species of veterinary interest. A deep knowledge of these issues is crucial for the use of phytocannabinoids for therapeutic purposes in animal species.

Indexed as

CannabinoidsEndocannabinoidsAnimalsCatsDogsHorsesReceptors, CannabinoidCannabinoidsEndocannabinoidsReceptors, CannabinoidCatDogECSHorsePhytocannabinoids

Identifiers

PMID39162768
PMCPMC11442603

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.