Evidence map›Paper›PMID 39162729›Full record

ArticleExperimental brain research2024

Changes in cerebral vascular reactivity following mild repetitive head injury in awake rats: modeling the human experience.

Nicole Bens, Praveen Kulkarni, Craig F Ferris

Abstract read
In one paragraph

Article in Experimental brain research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicole BensCenter for Translational Neuroimaging, Northeastern University, 360 Huntington Ave, Boston, MA, 02115, USA.
Praveen KulkarniCenter for Translational Neuroimaging, Northeastern University, 360 Huntington Ave, Boston, MA, 02115, USA.
Craig F FerrisCenter for Translational Neuroimaging, Northeastern University, 360 Huntington Ave, Boston, MA, 02115, USA. c.ferris@northeastern.edu.ORCID http://orcid.org/0000-0001-9744-5214

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The changes in brain function in response to mild head injury are usually subtle and go undetected. Physiological biomarkers would aid in the early diagnosis of mild head injury. In this study we used hypercapnia to follow changes in cerebral vascular reactivity after repetitive mild head injury. We hypothesized head injury would reduce vascular reactivity. Rats were maintained on a reverse light-dark cycle and head impacted daily at 24 h intervals over three days. All head impacts were delivered while rats were fully awake under red light illumination. There was no neuroradiological evidence of brain damage. After the 3rd impact rats were exposed to 5% CO

Indexed as

Disease Models, AnimalHypercapniaMagnetic Resonance ImagingRats, Sprague-DawleyWakefulnessAnimalsBrainCerebrovascular CirculationMaleOxygenRatsOxygenCerebral small vessel diseaseConcussionHypercapniaMomentum exchange

Identifiers

PMID39162729
PMCPMC11422282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.