Evidence map›Paper›PMID 39162522›Full record

ArticleMicrobiology spectrum2024

Oropharyngeal microbiome profiling and its association with age and heart failure in the elderly population from the northernmost province of China.

Jian Liu, Xiao-Yu He, Ke-Laier Yang, Yue Zhao, En-Yu Dai, Wen-Jia Chen, Aditya Kumar Raj, Di Li, Min Zhuang, Xin-Hua Yin and 1 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jian Liu *Department of Microbiology, Harbin Medical University, Harbin, China.ORCID 0000-0003-1615-3389
Xiao-Yu He *Department of Microbiology, Harbin Medical University, Harbin, China.
Ke-Laier Yang *Department of Endocrinology and Metabolism, Shenzhen University General Hospital, Shenzhen, China.
Yue Zhao *Department of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin, China.
En-Yu DaiDepartment of Microbiology, Harbin Medical University, Harbin, China.
Wen-Jia ChenDepartment of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Aditya Kumar RajDepartment of Microbiology, Harbin Medical University, Harbin, China.
Di LiDepartment of Microbiology, Harbin Medical University, Harbin, China.
Min ZhuangDepartment of Microbiology, Harbin Medical University, Harbin, China.
Xin-Hua YinDepartment of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin, China.ORCID 0000-0002-5874-1448
Hong LingDepartment of Microbiology, Harbin Medical University, Harbin, China.ORCID 0000-0002-1886-1242

Funding

Grant for Innovation Team Program of Heilongjiang ProvinceNational Science Foundation of China 81570437Shenzhen excellent science and technology innovation talent training project RCBS20221008093102010Shenzhen Science and Technology Program Project JCYJ20220531102612027
6 · The paper itself

Abstract

Respiratory tract infections are the most common triggers for heart failure in elderly people. The healthy respiratory commensal microbiota can prevent invasion by infectious pathogens and decrease the risk of respiratory tract infections. However, upper respiratory tract (URT) microbiome in the elderly is not well understood. To comprehend the profiles of URT microbiota in the elderly, and the link between the microbiome and heart failure, we investigated the oropharyngeal (OP) microbiome of these populations in Heilongjiang Province, located in the North-East of China, a high-latitude and cold area with a high prevalence of respiratory tract infection and heart failure. Taxonomy-based analysis showed that six dominant phyla were represented in the OP microbial profiles. Compared with young adults, the OP in the elderly exhibited a significantly different microbial community, mainly characterized by highly prevalent

Indexed as

BacteriaHeart FailureMicrobiotaOropharynxAdultAgedAged, 80 and overAge FactorsChinaFemaleHumansMaleMiddle AgedRespiratory Tract InfectionsRNA, Ribosomal, 16SYoung AdultRNA, Ribosomal, 16Shealthy agingheart failureoropharyngeal microbiomerespiratory tract

Identifiers

PMID39162522
PMCPMC11448084

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.