WQ-3810, a fluoroquinolone with difluoropyridine derivative as the R1 group exerts high potency against quinolone-resistant
Kentaro Koide, Hyun Kim, Matthew V X Whelan, Lawrence P Belotindos, Wimonrat Tanomsridachchai, Ruchirada Changkwanyeun, Masaru Usui, Tadhg Ó Cróinín, Jeewan Thapa, Chie Nakajima and 1 more
Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
11 authors.
Kentaro KoideDivision of Bioresources, Hokkaido University International Institute for Zoonosis Control, Sapporo, Japan.ORCID 0000-0002-9840-3689
Hyun KimDepartment of Bacteriology II, National Institute of Infectious Diseases, Musashimurayama, Japan.
Matthew V X WhelanSchool of Biomolecular and Biomedical Science, University College Dublin, Belfield, Ireland.
Lawrence P BelotindosDivision of Bioresources, Hokkaido University International Institute for Zoonosis Control, Sapporo, Japan.
Wimonrat TanomsridachchaiDivision of Bioresources, Hokkaido University International Institute for Zoonosis Control, Sapporo, Japan.
Ruchirada ChangkwanyeunFaculty of Public Health, Thammasat University, Pathum Thani, Thailand.
Masaru UsuiSchool of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan.
Tadhg Ó CróinínSchool of Biomolecular and Biomedical Science, University College Dublin, Belfield, Ireland.ORCID 0000-0003-1966-204X
Jeewan ThapaDivision of Bioresources, Hokkaido University International Institute for Zoonosis Control, Sapporo, Japan.ORCID 0000-0002-3447-6483
Chie NakajimaDivision of Bioresources, Hokkaido University International Institute for Zoonosis Control, Sapporo, Japan.
Yasuhiko SuzukiDivision of Bioresources, Hokkaido University International Institute for Zoonosis Control, Sapporo, Japan.ORCID 0000-0002-1313-1494
Funding
Japan Agency for Medical Research and Development (AMED) JP233fa627005 and JP20wm0125008Japan Society for the Promotion of Science (JSPS) 22K0599902
6 · The paper itself
Abstract
Quinolone-resistant IMPORTANCE: WQ-3810, a relatively new quinolone antibiotic, demonstrates exceptional antibacterial properties against certain pathogens in previous studies. However, its efficacy against quinolone-resistant
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
WQ-3810, a fluoroquinolone with difluoropyridine derivative as the R1 group exerts high potency against quinolone-resistant · full record | OpenQuestion