Evidence map›Paper›PMID 39162481›Full record

ArticleJournal of virology2024

Zebrafish

Guangqing Yu, Le Yuan, Xiong Li, Mingzhong Zuo, Rui Wang, Mengjuan Chen, Yuqing Liu, Xing Liu, Wuhan Xiao

Abstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guangqing Yu *College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, People's Republic of China.ORCID 0000-0003-4475-3613
Le Yuan *Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.
Xiong LiKey Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.
Mingzhong ZuoCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou, People's Republic of China.
Rui WangKey Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.
Mengjuan ChenCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou, People's Republic of China.
Yuqing LiuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou, People's Republic of China.
Xing LiuKey Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.ORCID 0000-0001-9338-7440
Wuhan XiaoKey Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.ORCID 0000-0002-2978-0616

Funding

China Postdoctoral Science Foundation (China Postdoctoral Foundation Project) 2021M701107MOST | National Natural Science Foundation of China (NSFC) 31721005MOST | National Natural Science Foundation of China (NSFC) 31830101MOST | National Natural Science Foundation of China (NSFC) 32102833
6 · The paper itself

Abstract

PHD1 is a member of the prolyl hydroxylase domain protein (PHD1-4) family, which plays a prominent role in the post-translational modification of its target proteins by hydroxylating proline residues. The best-characterized targets of PHD1 are hypoxia-inducible factor α (HIF-1α and HIF-2α), two master regulators of the hypoxia signaling pathway. In this study, we show that zebrafish phd1 positively regulates mavs-mediated antiviral innate immunity. Overexpression of

Indexed as

Adaptor Proteins, Signal TransducingImmunity, InnateRhabdoviridaeRhabdoviridae InfectionsUbiquitinationZebrafishZebrafish ProteinsAnimalsFish DiseasesHEK293 CellsHumansHydroxylationProtein Processing, Post-TranslationalSignal TransductionAdaptor Proteins, Signal TransducingMAVS protein, zebrafishZebrafish Proteinsantiviral responseinnate immunitymavsphd1SVCVzebrafish

Identifiers

PMID39162481
PMCPMC11406971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.