Evidence map›Paper›PMID 39162320›Full record

ArticleGeriatrics & gerontology international2024

Relationship between respiratory function assessed by spirometry and mild cognitive impairment among community-dwelling older adults.

Yuka Tachibana, Kayo Godai, Mai Kabayama, Yuya Akagi, Michiko Kido, Mariko Hosokawa, Hiroshi Akasaka, Yoichi Takami, Koichi Yamamoto, Saori Yasumoto and 6 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Geriatrics & gerontology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07620249 (The Effects of Combined Thoracic Expansion Exercises and Slow Diaphragmatic Breathing on Cognitive Function, Brain Activation, Psychological Status, and Head-Shoulder Posture in Healthy Adults), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07620249 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effects of Combined Thoracic Expansion Exercises and Slow Diaphragmatic Breathing on Cognitive Function, Brain Activation, Psychological Status, and Head-Shoulder Posture in Healthy Adults

TypeinterventionalSponsorNational Taiwan University Clinical Trial CenterRan2026 to 2027Enrolled60ConditionsDiaphragm PacingArmsthoracic expansion exercises and slow diaphragmatic breathing, Sham Block
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yuka TachibanaDivision of Health Sciences, Osaka University, Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0009-0003-6361-5598
Kayo GodaiDivision of Health Sciences, Osaka University, Graduate School of Medicine, Suita, Japan.
Mai KabayamaDivision of Health Sciences, Osaka University, Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0000-0003-1394-1152
Yuya AkagiDivision of Health Sciences, Osaka University, Graduate School of Medicine, Suita, Japan.
Michiko KidoDivision of Health Sciences, Osaka University, Graduate School of Medicine, Suita, Japan.
Mariko HosokawaDivision of Health Sciences, Osaka University, Graduate School of Medicine, Suita, Japan.
Hiroshi AkasakaDepartment of Geriatrics and General Medicine, Osaka University, Graduate School of Medicine, Suita, Japan.
Yoichi TakamiDepartment of Geriatrics and General Medicine, Osaka University, Graduate School of Medicine, Suita, Japan.
Koichi YamamotoDepartment of Geriatrics and General Medicine, Osaka University, Graduate School of Medicine, Suita, Japan.
Saori YasumotoDepartment of Human Sciences, Osaka University, Graduate School of Human Sciences, Suita, Japan.
Yukie MasuiTokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Kazunori IkebeDepartment of Removable Prosthodontics and Gerontology, Osaka University Graduate School of Dentistry, Suita, Japan.ORCID https://orcid.org/0000-0001-5696-6785
Yasumichi AraiCenter for Supercentenarian Medical Research, Keio University, School of Medicine, Tokyo, Japan.
Tatsuro IshizakiTokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.ORCID https://orcid.org/0000-0002-1277-7293
Yasuyuki GondoDepartment of Human Sciences, Osaka University, Graduate School of Human Sciences, Suita, Japan.
Kei KamideDivision of Health Sciences, Osaka University, Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0000-0003-1720-2218

Funding

Japan Society for the Promotion of Science KAKENHI 19K07888Japan Society for the Promotion of Science KAKENHI 19K11138Japan Society for the Promotion of Science KAKENHI A22Z034140Ministry of Health, Labor and Welfare Research on Policy Planning and Evaluation Program JPMH23AA2006Osaka University's International Joint Research Promotion Program Support Type ASupport for Pioneering Research Initiated by the Next Generation J219713005
6 · The paper itself

Abstract

aimAging is a major cause of cognitive dysfunction. It has also been reported that respiratory function may influence cognitive dysfunction. However, few studies have examined the relationship between cognitive function and respiratory function among community-dwelling older adults. This study aims to determine the relationship between respiratory function, assessed using spirometry, and mild cognitive impairment (MCI) in community-dwelling older adults.

methodsThis study included 419 participants aged 73 ± 1 years and 348 participants aged 83 ± 1 years from the SONIC cohort study (Septuagenarians Octogenarians Nonagenarians Investigation with Centenarians Study). Respiratory function was evaluated using %Vital Capacity (%VC), Forced Expiratory Volume 1 s (FEV

resultsThe MoCA-J score exhibited a declining trend as the airflow-limitation stage increased among study participants in the 83 ± 1 age group. The presence of airflow limitation was associated with MCI in the 83 ± 1 age group. Among the indicators of each respiratory function, low %PEF was found to be associated with an increased rate of MCI. Furthermore, low %VC has also been suggested to be associated with an increased rate of MCI in the 83 ± 1 age female group.

conclusionsAdvanced airflow-limitation stages may exacerbate cognitive dysfunction in community-dwelling older adults. The presence of airflow limitation and low %VC may also be associated with cognitive dysfunction in older women. Consequently, reduced respiratory function may potentially be associated with MCI in community-dwelling older adults. Geriatr Gerontol Int 2024; 24: 1001-1007.

Indexed as

Cognitive DysfunctionIndependent LivingSpirometryAgedAged, 80 and overCohort StudiesFemaleForced Expiratory VolumeGeriatric AssessmentHumansJapanMaleRespiratory Function TestsVital Capacitycognitive agingepidemiologypulmonary

Identifiers

PMID39162320
PMCPMC11503567

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.