Evidence map›Paper›PMID 39161652›Full record

ArticleFrontiers in neuroscience2024

Scheduled feeding improves sleep in a mouse model of Huntington's disease.

Emily Chiem, Kevin Zhao, Derek Dell'Angelica, Cristina A Ghiani, Ketema N Paul, Christopher S Colwell

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Emily ChiemDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, United States.
Kevin ZhaoDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, United States.
Derek Dell'AngelicaDepartment of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, United States.
Cristina A GhianiDepartment of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, United States.
Ketema N PaulDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, United States.
Christopher S ColwellDepartment of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, United States.

Funding

UCLA IDDRC: Translational CoreP50HD103557 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Peyman Golshani, SUMA JACOB · 2020 to 2026
$9.6M
The impact of sex chromosomes on the ability to recover from sleep lossR01NS078410 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PAUL, KETEMA N · 2012 to 2025
$3.7M
Time restricted feeding rescues circadian and motor dysfunction in a mouse model of Huntington's diseaseR21NS115041 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COLWELL, CHRISTOPHER SCOTT, PAUL, KETEMA N · 2020 to 2021
$547k
NICHD NIH HHS P50 HD103557NINDS NIH HHS R01 NS078410NINDS NIH HHS R21 NS115041
6 · The paper itself

Abstract

Sleep disturbances are common features of neurodegenerative disorders including Huntington's disease (HD). Sleep and circadian disruptions are recapitulated in animal models, providing the opportunity to evaluate the effectiveness of circadian interventions as countermeasures for neurodegenerative disease. For instance, time restricted feeding (TRF) successfully improved activity rhythms, sleep behavior and motor performance in mouse models of HD. Seeking to determine if these benefits extend to physiological measures of sleep, electroencephalography (EEG) was used to measure sleep/wake states and polysomnographic patterns in male and female wild-type (WT) and bacterial artificial chromosome transgenic (BACHD) adult mice, under TRF and

Indexed as

BACHDEEGHuntington’s diseasesexsleeptime restricted feeding

Identifiers

PMID39161652
PMCPMC11330895

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.