Evidence map›Paper›PMID 39161638›Full record

ArticleFrontiers in pediatrics2024

Risk of low levels of blood group antibodies mediating hemolysis in ABO-incompatible neonates with negative three hemolysis tests.

Hongxing Lin, Pingxiang Luo, Chen Liu, Xiaosong Lin, Chengwen Que, Wenhui Zhong

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. ABO Incongruency Increases Risk for Necrotizing Enterocolitis in Preterm Neonates.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hongxing LinDepartment of Blood Transfusion, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China.
Pingxiang LuoDepartment of Neonatology, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China.
Chen LiuDepartment of Blood Transfusion, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China.
Xiaosong LinClinical Laboratory, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China.
Chengwen QueClinical Laboratory, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China.
Wenhui ZhongDepartment of Blood Transfusion, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the risk of low-level blood group antibody-mediated hemolysis in ABO-incompatible newborns with negative three hemolysis tests, aiming to assist in the identification and management of neonatal jaundice. Methods: A retrospective case-control study was performed in 892 children with jaundice. The patients were divided into three groups: group I, ABO compatible, negative three hemolysis tests; group II, ABO incompatible, negative three hemolysis tests; and group III, ABO incompatible, positive three hemolysis tests. We analyzed the differences in clinical data, blood routine and biochemical laboratory results. Results: (1) Patients in group II had higher levels of mean corpuscular volume (MCV), standard deviation of red blood cell volume distribution width (RDW-SD), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alkaline phosphatase (ALP), and bile acid (BA) than those in group I ( Conclusion: Low-level blood group antibody-mediated hemolysis may occur in ABO-incompatible neonates even when three hemolysis tests are negative. Changes in liver function parameters must be monitored. The combination of MCHC, RDW-CV, and RET% can be used to improve the detection rate of HDN.

Indexed as

ABO hemolytic disease of the newbornblood group antibodiescoefficient of variation of red blood cell volume distribution widthmean corpuscular hemoglobin concentrationthree hemolysis tests

Identifiers

PMID39161638
PMCPMC11330777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.