Evidence map›Paper›PMID 39161554›Full record

ArticleBMJ open sport & exercise medicine2024

DOSage of Exercise for chronic low back pain disorders (DOSE): protocol for a systematic review with dose-response network meta-analysis.

Nitin Kumar Arora, Lars Donath, Patrick J Owen, Clint T Miller, Svenja Kaczorowski, Tobias Saueressig, Hugo Pedder, Niamh L Mundell, Scott D Tagliaferri, Ashish Diwan and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open sport & exercise medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Nitin Kumar AroraHochschule für Gesundheit, Department of Applied Health Sciences, Division of Physiotherapy, University of Applied Sciences, Bochum, Germany.ORCID 0000-0002-8841-2549
Lars DonathDepartment of Intervention Research in Exercise Training, German Sport University Cologne, Koln, Germany.ORCID 0000-0001-6039-0141
Patrick J OwenEastern Health Emergency Medicine Program, Melbourne, Victoria, Australia.ORCID 0000-0003-3924-9375
Clint T MillerInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia.ORCID 0000-0001-7743-6986
Svenja KaczorowskiHochschule für Gesundheit, Department of Applied Health Sciences, Division of Physiotherapy, University of Applied Sciences, Bochum, Germany.ORCID 0000-0001-8794-3252
Tobias SaueressigPhysio Meets Science GmbH, Leimen, Germany.ORCID 0000-0002-3332-3856
Hugo PedderPopulation Health Sciences, University of Bristol, Bristol, UK.ORCID 0000-0002-7813-3749
Niamh L MundellInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia.
Scott D TagliaferriCentre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0003-3669-4131
Ashish DiwanSt. George Hospital, Department of Orthopaedic Surgery, Spine Service, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0003-1037-8421
Xiaolong ChenSt. George Hospital, Department of Orthopaedic Surgery, Spine Service, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0003-2083-0549
Xiaohui ZhaoXi'an University of Architecture & Technology, Beilin, China.ORCID 0000-0002-0406-9342
Eva-Maria HuesslerInstitute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany.ORCID 0000-0002-8144-5428
Katja EhrenbrusthoffHochschule für Gesundheit, Department of Applied Health Sciences, Division of Physiotherapy, University of Applied Sciences, Bochum, Germany.ORCID 0000-0003-1667-8943
Jon J FordDiscipline of Physiotherapy, School of Allied Health, Human Services & Sport, La Trobe University, Bundoora, Victoria, Australia.ORCID 0000-0001-5524-190X
Andrew J HahneDiscipline of Physiotherapy, School of Allied Health, Human Services & Sport, La Trobe University, Bundoora, Victoria, Australia.ORCID 0000-0002-6227-5339
Ludwig HammelDeutsche Vereinigung Morbus Bechterew e.V. (DVMB), 97421 Schweinfurt, Germany.
Heike NordaUVSD SchmerzLOS e.V. (Unabhängige Vereinigung aktiver Schmerzpatienten in Deutschland), 24534 Neumünster, Germany.
Daniel L BelavyHochschule für Gesundheit, Department of Applied Health Sciences, Division of Physiotherapy, University of Applied Sciences, Bochum, Germany.ORCID 0000-0002-9307-832X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic low back disorders are the leading cause of direct and indirect healthcare burden globally. Exercise training improves pain intensity, mental health and physical function. However, the optimal prescription variables are unknown. We aim to compare the efficacy of various exercise dosages for chronic low back disorders to identify the optimal prescription variables. Six databases (Medline, SPORTDiscus, CINAHL, PsycINFO, EMBASE and CENTRAL), trial registries (ClinicalTrials.gov and WHO International Clinical Trials Registry Platform) and reference lists of prior systematic reviews will be searched, and we will conduct forward and backward citation tracking. We will include peer-reviewed randomised controlled trials (individual, cluster or cross-over trials) published in English or German language comparing exercise training to other exercise training or non-exercise training interventions (conservative, non-surgical, non-pharmacological, non-invasive treatments, placebo, sham, usual/standard care, no-treatment control, waitlist control) in adults with chronic low back disorders. Outcomes will include pain intensity, disability, mental health, adverse events, adherence rate, dropout rate and work capacity. Version 2 of the Cochrane risk-of-bias tool will be employed. The dose will be categorised as cumulative dose (total and weekly minutes of exercise training) and individual dose prescription variables (intervention duration, session duration, frequency and intensity). Dose-response model-based network meta-analysis will be used to assess the comparative efficacy of different exercise doses to determine a dose-response relationship. The certainty of evidence will be assessed using the Grading of Recommendations Assessment, Development and Evaluation. Information about optimal exercise training dosage will help in enhancing treatment outcomes.

Indexed as

Back injuriesEvidence based reviewExercise rehabilitationMeta-analysisPhysical activity

Identifiers

PMID39161554
PMCPMC11331831

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.