ArticleCureus2024
Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis (SAPHO) Syndrome Mimicking Bone Metastases in the Spine: A Presentation of Two Cases and Literature Review.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- CT and MRI features of SAPHO syndrome: a report of 6 cases.BMC musculoskeletal disorders · 2026Article
- From misdiagnosis to definitive diagnosis of SAPHO syndrome during a routine health check-up: a case report and literature review.Frontiers in medicine · 2026Article
- Article
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5 authors.
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Abstract
Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome is a rare disorder of unknown etiology with heterogeneous clinical manifestations. We describe two cases of patients diagnosed with SAPHO syndrome mimicking spinal bone metastases. A literature review was conducted to identify similar previously reported cases. The first patient was a 56-year-old woman with progressive back pain for six months who was referred to the neurosurgery department for suspected spinal metastases. A spinal CT scan revealed hyperdense lesions at T10 and hyperdense changes in the lumbar vertebrae. Spinal MRI demonstrated bone marrow edema that was hypointense on T1-weighted imaging and hyperintense on T2-weighted imaging in multiple thoracic vertebrae, and the PET/CT showed multiple skeletal lesions affecting the spine with low-to-moderate
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