Evidence map›Paper›PMID 39161475›Full record

ArticleCureus2024

Distal Femur Cemented Modular Prosthesis Failure Causing a Medical Device-Related Adverse Event: A Report of a Rare Case.

Arohi Agarwal, Krishna Singh, Samyak Jain, Gagan Singh, Puneet Dhamija, Piyush Mittal

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arohi AgarwalMateriovigilance, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.
Krishna SinghMateriovigilance, Indian Pharmacopoeia Commission, Ministry of Health and Family Welfare, Ghaziabad, IND.
Samyak JainMateriovigilance, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.
Gagan SinghMateriovigilance, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.
Puneet DhamijaPharmacology, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.
Piyush MittalPharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Moradabad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A distal femoral cemented modular prosthesis is a viable option for post-bone tumor and limb salvage procedures. The major reasons for implant failures are the poor quality of implants, mechanical stress, biochemical reactions, and extended period of the implant in vivo use. Rare incidences have been reported of distal femur prosthesis implant malfunctioning in a subject having osteosarcoma. Common adverse events associated with implant failure include surgical site infections, swelling, pain, revision of the surgical procedure, cyst formation, and build-up of metal debris on soft tissues. Our case report summarizes gross malfunctioning of a distal femur cemented modular prosthesis experienced by a 24-year-old post-operated osteosarcoma patient who developed excruciating sudden pain and the inability to bear weight on the right leg, with the sudden onset of these symptoms developing while turning in bed.

Indexed as

distal femur prosthesismegaprosthesismesenchymal cellsosteoblastosteosarcoma

Identifiers

PMID39161475
PMCPMC11332967

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.