Evidence map›Paper›PMID 39161386›Full record

ReviewFrontiers in oncology2024

Advanced, recurrent, and persistent cervical cancer management: in the era of immunotherapy.

Tatiana Galicia-Carmona, Eder Alexandro Arango-Bravo, Jaime A Coronel-Martínez, Lucely Cetina-Pérez, Elva G Vanoye-Carlo, Ricardo Villalobos-Valencia, José A García-Pacheco, Patricia Cortés-Esteban

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tatiana Galicia-CarmonaDepartment of Clinical Research, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico.
Eder Alexandro Arango-BravoDepartment of Clinical Research, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico.
Jaime A Coronel-MartínezDepartment of Clinical Research, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico.
Lucely Cetina-PérezDepartment of Clinical Research, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico.
Elva G Vanoye-CarloDepartment of Surgical Oncology, Hospital Regional de Alta Especialidad de la Península de Yucatán, Yucatán, Mexico.
Ricardo Villalobos-ValenciaDepartment of Medical Oncology, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
José A García-PachecoNSR III Researcher assistant, Consejo Nacional de Humanidades, Ciencias y Tecnologías(CONACYT), Mexico City, Mexico.
Patricia Cortés-EstebanDepartment of Medical Oncology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer constitutes a significant health burden for women worldwide despite being preventable by vaccination and screening. Advanced stages of the disease are associated with a poor prognosis, and treatment approaches have seen little change over several decades, resulting in an overall survival rate of no more than 17 months. Additionally, there are limited options for second-line treatment. The urgent need for innovative and effective therapies to improve the outlook for this group of patients, along with an enhanced understanding of the interactions between the disease and the host's immune system, has propelled immunotherapy into a rapidly advancing field with notable achievements. Among various immunotherapeutic approaches, immune checkpoint inhibitors emerge as the most advanced treatment option. Clinical trials assessing these inhibitors as single agents or in combination with chemotherapy show promising results. As immunotherapy begins to redefine standards of care for metastatic, recurrent, or persistent cervical cancer, this review addresses recent advances and current recommendations for its management in both first and second-line treatment. The goal is to provide insights into the evolving landscape of cervical cancer treatment, specifically focusing on immunotherapeutic interventions.

Indexed as

cervical cancercheckpoint inhibitorsimmunotherapymetastatic cervical cancerrecurrent and persistent disease

Identifiers

PMID39161386
PMCPMC11330775

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.