Evidence map›Paper›PMID 39161142›Full record

ArticleCurrent topics in medicinal chemistry2024

Melanin Synthesized by the Endophytic

Khaled M Elattar, Abeer A Ghoniem, Abdulaziz A Al-Askar, Usama Bhgat El-Gazzar, Mohammed S El-Hersh, Elsherbiny A Elsherbiny, Noha M Eldadamony, WesamEldin I A Saber

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Article in Current topics in medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Bioinspired Ag/CeOScientific reports · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. EndophyticFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khaled M ElattarUnit of Genetic Engineering and Biotechnology, Faculty of Science, Mansoura University, El-Gomhoria Street, Mansoura, 35516, Egypt.
Abeer A GhoniemMicrobial Activity Unit, Department of Microbiology, Soils, Water and Environment Research Institute, Agricultural Research Center, Giza12619, Egypt.
Abdulaziz A Al-AskarBotany and Microbiology Department, Faculty of Science, King Saud University, Riyadh11451, Saudi Arabia.
Usama Bhgat El-GazzarDepartment of Medical Biochemistry, Damietta Faculty of Medicine, Al-Azhar University, Egypt.
Mohammed S El-HershMicrobial Activity Unit, Department of Microbiology, Soils, Water and Environment Research Institute, Agricultural Research Center, Giza12619, Egypt.
Elsherbiny A ElsherbinyDepartment of Biology, Rheinland-Pfälzische Technische Universität Kaiserslautern (RPTU), 67663Kaiserslautern, Germany.
Noha M EldadamonySeed Pathology Department, Plant Pathology Research Institute, Agricultural Research Center, Giza12619, Egypt.
WesamEldin I A SaberMicrobial Activity Unit, Department of Microbiology, Soils, Water and Environment Research Institute, Agricultural Research Center, Giza12619, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study explores the potential of the endophytic fungus Aureobasidium pullulans AKW for melanin production and its anticancer activity.

methodWe report a significant achievement:

resultOur results demonstrate that

conclusionThe selective activity of the current melanin towards cancer cells, its ability to induce apoptosis, and its relatively low toxicity towards normal cells warrant further investigation for its development as a novel therapeutic option.

Indexed as

Antineoplastic AgentsAntioxidantsAureobasidiumMelaninsApoptosisAscomycotaCell Line, TumorCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMolecular StructureStructure-Activity RelationshipWound HealingAntineoplastic AgentsAntioxidantsMelaninsAntibacterialAnticancer.AntiproliferativeAntitumorApoptosisEndophytic

Identifiers

PMID39161142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.