ArticleSurgical endoscopy2024
Risk factors for and treatment of anastomotic strictures after Ivor Lewis esophagectomy.
Article in Surgical endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06662513 (An Australian Regional Hospital's Oesophagectomy Outcomes), which is not on this map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Australian Regional Hospital's Oesophagectomy Outcomes
Who cites it
5 citing papers in PubMed.
- Advances in the treatment of postoperative anastomotic strictures in esophageal cancer a comparative analysis of the efficacy of endoscopic versus interventional dilatation.Langenbeck's archives of surgery · 2026Review
- OTSC combined with jejunal mucosal ESD for closure of jejunal dilated blind pouch and anastomotic metal stent placement in the treatment of post-oesophagojejunostomy stricture: a case report (with video).Frontiers in medicine · 2026Article
- The Rule for Good Anastomosis: A Golden Ratio Between Thickness and Diameter.Annals of surgical oncology · 2025Article
- Pathophysiology of anastomotic stricture following rectal anastomosis: Insights into mechanisms, risk factors, and preventive strategies.World journal of gastrointestinal pathophysiology · 2025Review
- An Australian regional hospital's oesophagectomy experience: A 10-year case series from Tasmania.Surgery in practice and science · 2025Article
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Authors and funding
5 authors.
Funding
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Abstract
introductionAnastomotic strictures following esophagectomy occur frequently and impact on nutrition and quality of life. Although strictures are often attributed to ischemia and anastomotic leaks, the role of anastomosis size and pyloroplasty is not well evaluated. Our study aims to assess the rate of and risk factors for anastomotic stricture following esophagectomy, and the impact of treatment with regular endoscopic balloon dilatations.
methodsConsecutive patients (n = 207) undergoing Ivor Lewis esophagectomy performed by two surgeons at our institution were included. Data on patient demographics, surgical outcomes and anastomotic strictures were recorded. Relationship of anastomotic strictures with circular stapler size, pyloroplasty and anastomotic leak was analyzed. Treatment of strictures with endoscopic balloon dilatation was reviewed and percentage weight loss at 1 year was evaluated.
resultsAnastomotic strictures occurred in 17.4% of patients. Patient demographics between those with and without stricture were similar. Stricture rate was similar in patients with or without pyloroplasty (13.9% vs 21.7%, respectively, p = 0.14) and in those with or without an anastomotic leak (25.0% vs 16.6%, respectively, p = 0.345). Stricture risk increased with smaller sized stapler (25 mm = 33.3%, 28 mm = 15.3%, 31 mm = 4.8%; p = 0.027). The median number of dilatations required to fully treat strictures was 2 (IQR: 1-3). The median length of time from surgery to first dilatation was 2.9 months (IQR: 2.0-4.7) and to last dilatation was 6.1 months (IQR: 4.8-10.0). Median maximum dilatation diameter was 20 mm (IQR: 18.0-20.0). There were no complications from dilatations. Percentage weight loss at 1 year in patients with strictures was similar to those without strictures (8.7% vs 11.1%, respectively, p = 0.090).
conclusionsPost-esophagectomy anastomotic strictures are common and not necessarily related to anastomotic leaks or absence of pyloroplasty. Smaller anastomosis size was strongly linked with stricture formation. A driven approach with regular endoscopic balloon dilation is safe and effective in treating these strictures with no excess weight loss at 1 year once treated.
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