Evidence map›Paper›PMID 39160172›Full record

ArticleScientific reports2024

Quality by design approach of apocynin loaded clove oil based nanostructured lipid carrier as a prophylactic regimen in hemorrhagic cystitis in vitro and in vivo comprehensive study.

Amir Elsayed Maghrabia, Mariza Fouad Boughdady, Sherry Mohamed Khater, Irhan Ibrahim ِِAbu Hashim, Mahasen Mohammed Meshali

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amir Elsayed MaghrabiaDepartment of Pharmaceutics, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. amir2007_pharm@yahoo.com.ORCID 0000-0002-7373-4756
Mariza Fouad BoughdadyDepartment of Pharmaceutics, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
Sherry Mohamed KhaterDepartment of Clinical Pathology, Urology and Nephrology Center, Mansoura University, Mansoura, 35516, Egypt.
Irhan Ibrahim ِِAbu HashimDepartment of Pharmaceutics, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
Mahasen Mohammed MeshaliDepartment of Pharmaceutics, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apocynin (APO) is a naturally occurring acetophenone with eminent anti-inflammatory and anti-oxidant peculiarities. It suffers from poor bioavailability due to low aqueous solubility. Herein, APO was loaded in a Clove oil (CO) based Nanostructured lipid carrier (NSLC) system using a simple method (ultrasonic emulsification) guided by a quality-by-design approach (2

Indexed as

AcetophenonesClove OilDrug CarriersAnimalsCell Line, TumorCystitis, HemorrhagicHemorrhageHumansLipidsMaleNanostructuresParticle SizeRatsRats, WistarAcetophenonesClove OilDrug CarriersLipidsApocyninBladder cancerClove oilCystitisNanostructured lipid carrierPhytopharmaceuticals

Identifiers

PMID39160172
PMCPMC11333711

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.