Evidence map›Paper›PMID 39159989›Full record

ArticleBJGP open2025

Utilisation and consequences of CRP point-of-care-testing in primary care practices: a real-world multicentre observational study with 1740 patient cases in Germany.

Robby Markwart, Lena-Sophie Lehmann, Markus Krause, Paul Jung, Liliana Rost, Susanne Doepfmer, Lisa Kuempel, Doreen Kuschick, Kahina J Toutaoui, Christoph Heintze and 2 more

Abstract read
In one paragraph

Article in BJGP open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Robby MarkwartInstitute of General Practice and Family Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Lena-Sophie LehmannInstitute of General Practice and Family Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Markus KrauseInstitute of General Practice and Family Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Paul JungInstitute of General Practice and Family Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Liliana RostInstitute of General Practice and Family Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Susanne DoepfmerCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of General Practice, Berlin, Germany.ORCID https://orcid.org/0000-0003-4263-2682
Lisa KuempelCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of General Practice, Berlin, Germany.
Doreen KuschickCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of General Practice, Berlin, Germany.
Kahina J ToutaouiCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of General Practice, Berlin, Germany.
Christoph HeintzeCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of General Practice, Berlin, Germany.
Jutta BleidornInstitute of General Practice and Family Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Florian WolfInstitute of General Practice and Family Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Germany florian.wolf@med.uni-jena.de.ORCID https://orcid.org/0000-0002-0961-1057

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundC-reactive protein point-of-care tests (CRP-POCTs) can support GPs' clinical decision making but they are not widely used in German general practices.

aimTo investigate the utilisation of semi-quantitative CRP-POCTs in routine primary care. DESIGN &

settingProspective observational study in 49 general practices in Germany (from November 2022-April 2023).

methodGPs were provided with CRP-POCTs and collected data for each CRP-POCT use, with standardised data-collection sheets.

resultsData from 1740 CRP-POCT uses were recorded. GPs employed CRP-POCTs mainly for patients with respiratory tract infections (RTIs; 71.2% of all cases) and to a lesser extent for gastrointestinal infections (GIs; 10.4%). In RTIs, CRP-POCTs were frequently used to distinguish between bacterial and viral aetiology (60.8%) and to guide decisions on antibiotic prescribing (62.8%). In GIs, CRP-POCTs were mainly used to rule out severe disease progressions (53.2%) and for decisions on further diagnostic procedures (45.6%). In RTIs, CRP-POCTs influenced antibiotic prescribing in 77.5% of the cases (32.3% in favour versus 45.2% waiver). In GIs, CRP levels mainly affected decisions on further diagnostic procedures. GPs reported that CRP-POCTs were helpful in 88.6% of all cases.

conclusionWhen available, German GPs predominantly use semi-quantitative CRP-POCTs to guide decisions on antibiotic prescribing in patients with RTIs. CRP-POCT use improves clinical decision making and increases the GP's clinical confidence.

Indexed as

C-reactive proteindiagnosisfamily medicinegeneral practitionersinfectious illnesspoint-of-care testingprimary healthcare

Identifiers

PMID39159989
PMCPMC12138004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.