Evidence map›Paper›PMID 39159704›Full record

ArticleNeuroImage2024

Multicompartment imaging of the brain using a comprehensive MR imaging protocol.

James Lo, Kevin Du, David Lee, Chun Zeng, Jiyo S Athertya, Melissa Lou Silva, Reese Flechner, Graeme M Bydder, Yajun Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

James LoDepartment of Radiology, University of California, San Diego, CA, USA; Department of Bioengineering, University of California, San Diego, CA, USA.
Kevin DuDepartment of Radiology, University of California, San Diego, CA, USA.
David LeeDepartment of Radiology, University of California, San Diego, CA, USA.
Chun ZengDepartment of Radiology, University of California, San Diego, CA, USA.
Jiyo S AthertyaDepartment of Radiology, University of California, San Diego, CA, USA.
Melissa Lou SilvaDepartment of Radiology, University of California, San Diego, CA, USA.
Reese FlechnerDepartment of Radiology, University of California, San Diego, CA, USA; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Graeme M BydderDepartment of Radiology, University of California, San Diego, CA, USA.
Yajun MaDepartment of Radiology, University of California, San Diego, CA, USA. Electronic address: yam013@ucsd.edu.

Funding

Ultrashort Echo Time Magnetic Resonance Imaging of the Lumbar Intervertebral Disc.R01AR079484 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Yajun Ma · 2022 to 2026
$2.7M
Quantitative UTE MR Imaging of Myelin: Novel Biomarkers for Alzheimer's DiseaseRF1AG075717 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2022 to 2022
$2.3M
Comparison of direct and indirect magnetic resonance imaging of myelin in Alzheimer's diseaseF32AG082458 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ATHERTYA, JIYO S · 2023 to 2025
$256k
Developing MRI Biomarkers of Myelin and Iron in Veterans with Traumatic Brain InjuryI01CX002211 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Jiang Du · 2021 to 2026
–
CSRD VA I01 CX002211NIAMS NIH HHS R01 AR079484NIA NIH HHS F32 AG082458NIA NIH HHS RF1 AG075717
6 · The paper itself

Abstract

In this study, we describe a comprehensive 3D magnetic resonance imaging (MRI) protocol designed to assess major tissue and fluid components in the brain. The protocol comprises four different sequences: 1) magnetization transfer prepared Cones (MT-Cones) for two-pool MT modeling to quantify macromolecular content; 2) short-TR adiabatic inversion-recovery prepared Cones (STAIR-Cones) for myelin water imaging; 3) proton-density weighted Cones (PDw-Cones) for total water imaging; and 4) highly T

Indexed as

BrainMagnetic Resonance ImagingMultiple SclerosisAdultFemaleHumansImaging, Three-DimensionalMaleMiddle AgedMyelin SheathYoung AdultBrainConesMT modelingMulticompartmentMyelin content

Identifiers

PMID39159704
PMCPMC11629713

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.